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针灸治疗帕金森病便秘的机制研究现状与展望。

Research status and prospect on the mechanisms of acupuncture and moxibustion treatment for constipation of Parkinson's disease.

机构信息

Beijing Key Laboratory for Acupuncture-Moxibustion Neuro-modulation, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China.

Department of Chinese Medicine, Community Healthcare Center of Shangzhuang Town, Haidian District, Beijing 100053.

出版信息

Zhen Ci Yan Jiu. 2023 Oct 25;48(10):1055-1061. doi: 10.13702/j.1000-0607.20230276.

DOI:10.13702/j.1000-0607.20230276
PMID:37879957
Abstract

Constipation may accelerate the progression of Parkinson's disease (PD). The quality of life in PD patients can be significantly improved when constipation is treated, hence the disease progression may be delayed. At present, the mechanism research is still at the initial stage for acupuncture in treatment of PD, focusing on neurohumoral factors, intestinal flora, bacterial fermentation products and intestinal inflammation; and there are the problems such as single intervention, thinking limitation and insufficient cooperation among disciplines. This paper systematically reviews the mechanism research progress of acupuncture for the treatment of constipation in PD so as to provide the references for the subsequent studies.

摘要

便秘可能会加速帕金森病(PD)的进展。治疗便秘可显著改善 PD 患者的生活质量,从而可能延缓疾病进展。目前,针刺治疗 PD 的机制研究仍处于起步阶段,主要集中在神经体液因素、肠道菌群、细菌发酵产物和肠道炎症方面;并且存在干预手段单一、思维局限以及学科间合作不足等问题。本文系统地综述了针刺治疗 PD 便秘的作用机制研究进展,以期为后续研究提供参考。

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