Pharmacology, AIIMS Kalyani, Basantapur, Saguna, West Bengal, India.
Microbiology, AIIMS Kalyani, Basantapur, Saguna, West Bengal, India.
Pediatr Res. 2024 Jan;95(2):464-479. doi: 10.1038/s41390-023-02866-x. Epub 2023 Oct 25.
This review utilizes quatitative methods and bibliometric data to analyse the trends of emerging and re-emerging vector-borne diseases, with a focus on their impact on pediatric population. To conduct this analysis, a systematic search of PubMed articles from the past two decades was performed, specifically looking at 26 different vector-borne viruses listed in WHO and CDC list of vector-borne viruses. The review found that diseases like Dengue, Zika, West Nile, and Chikungunya were frequently discussed in the literature. On the other hand, diseases such as Tick-borne encephalitis, Rift Valley fever, Venezuelan equine encephalitis, Sindbis fever, Venezuelan equine encephalitis, Ross River virus, and Eastern equine encephalitis showed an upward trend in publications, indicating potential resurgence. In addition to discussing trends and patterns, the review delves into the clinical manifestations and long-term effects of the top 10 viruses in children. It highlights various factors including deforestation, urbanization, global travel, and immunosuppression that contribute to disease emergence and resurgence. To effectively combat these vector-borne diseases, continuous surveillance is crucial. The review also emphasizes the importance of increased vaccination efforts and targeted research to address the health challenges they pose. IMPACT: This review employs quantitative analysis of publications to elucidate trends in emerging pediatric vector-borne viral diseases over two decades. Dengue, the most prevalent of these diseases, has spread to new regions. New strains of Japanese Encephalitis have caused outbreaks. Resurgence of Tick-borne Encephalitis, West Nile, and Yellow Fever due to vaccine hesitancy has also transpired. Continuous global surveillance, increased vaccination, and research into novel therapeutics are imperative to combat the substantial morbidity and mortality burden these diseases pose for children worldwide.
本综述利用定量方法和文献计量学数据分析新发和再发的虫媒病毒病趋势，重点关注其对儿科人群的影响。为进行此项分析，我们对过去二十年中来自 PubMed 的文章进行了系统检索，具体针对世界卫生组织和疾病预防控制中心列出的 26 种不同虫媒病毒进行分析。综述发现，登革热、寨卡、西尼罗河和基孔肯雅热等疾病在文献中经常被讨论。另一方面，诸如蜱传脑炎、裂谷热、委内瑞拉马脑炎、辛德毕斯热、委内瑞拉马脑炎、罗斯河病毒和东部马脑炎等疾病的出版物呈上升趋势，表明有潜在的再发。除了讨论趋势和模式外，该综述还深入探讨了前 10 种儿童虫媒病毒的临床表现和长期影响。它强调了森林砍伐、城市化、全球旅行和免疫抑制等各种因素导致疾病的出现和再发。为有效应对这些虫媒病毒病，持续监测至关重要。该综述还强调了增加疫苗接种力度和针对性研究的重要性，以应对它们给儿童健康带来的挑战。
本综述采用出版物的定量分析阐明了过去二十年中儿科新发虫媒病毒病的趋势。其中最常见的登革热已传播到新的地区。新型日本脑炎已引发暴发。由于疫苗犹豫，蜱传脑炎、西尼罗河和黄热病的再次出现也随之发生。持续的全球监测、增加疫苗接种以及针对新型治疗方法的研究对于应对这些疾病给全世界儿童带来的巨大发病率和死亡率负担至关重要。
