Parkes H G
IARC Sci Publ (1971). 1979(25):47-58.
The recognition of an increasing number of environmental and occupational factors imvolved in cancer etiology indicates the urgent need for more effective identification and control procedures. On the evidence of experience derived from the historical example of occupational bladder cancer, it is suggested that the problems of identification and control require an integrated approach which must involve the toxicity screening of industrial materials, the environmental screening of the industrial process and the epidemiological screening of those who work in industry. Such a programme will depend for its success upon the cooperation and understanding of all concerned, and the need for consultation and the full provision of information is stressed. Benefits are indicated which might ultimately accrue from the establishment of a computerized data bank in which the results of toxicological, epidemiological and carcinogenicity investigations have been accumulated and collated under the auspices of an international agency.
对越来越多与癌症病因相关的环境和职业因素的认识表明,迫切需要更有效的识别和控制程序。根据职业性膀胱癌这一历史实例所获得的经验证据,有人提出,识别和控制问题需要一种综合方法,该方法必须包括对工业材料的毒性筛查、工业生产过程的环境筛查以及对产业工人的流行病学筛查。这样一个项目的成功将取决于所有相关方的合作与理解,强调了协商的必要性以及充分提供信息的重要性。有人指出,在一个国际机构的支持下建立一个计算机化数据库,积累和整理毒理学、流行病学和致癌性调查结果,最终可能会带来好处。