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伴有固有层浸润的去分化浅表性膀胱癌(pT1 GIII)

[Dedifferentiated superficial bladder cancer with invasion of the lamina propria (pT1 GIII)].

作者信息

Flamm J

出版信息

Z Urol Nephrol. 1986 Sep;79(9):511-6.

PMID:3788301
Abstract

On the basis of a retrospective investigation in 45 patients with a carcinoma of the epithelium of the urinary tract pT1 GIII and primary conservative therapy the prognostically relevant factors are controlled. The primary multifocality, the positive dysplastic findings of the biopsies of the mucous membrane and the lacking tumour-associated cell infiltration appeared as high risk for recidivation and tumour progression. The size of the tumour was prognostically not relevant. The rate of recidivations was 53.3%, the tumour progression 37.5%. The 3-year survival rate was 65%, the 5-year rate survival 47%. A conservative therapy of the pT1 GIII tumour is recommended, but at the same time a possibly close-meshed control particularly of the high-risk group is demanded.

摘要

基于对45例pT1 GIII期尿路上皮癌患者进行的回顾性调查及原发性保守治疗,对预后相关因素进行了分析。原发性多灶性、黏膜活检中阳性发育异常表现以及缺乏肿瘤相关细胞浸润被视为复发和肿瘤进展的高风险因素。肿瘤大小在预后方面无关紧要。复发率为53.3%,肿瘤进展率为37.5%。3年生存率为65%,5年生存率为47%。推荐对pT1 GIII期肿瘤进行保守治疗,但同时需要对高风险组进行可能更为密集的监测。

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