Abtahi N S, Ghezelayagh Z, Nemati I, Eivazkhani F, Farzaneh P, Shahverdi A, Goudarzi G R, Pedram A, Amirchaghmaghi E, Valojerdi M R, Silber S, Fathi R
Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Human and Animal Cell Bank, Iranian Biological Resource Center (IBRC); Futures Studies Office, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Cryo Letters. 2023 Jul-Aug;44(4):185-196.
Cryopreservation has been used over many decades for the maintenance of viable biological specimens. Its expansion into the area of fertility preservation has been a natural outcome of the increased risks to human fertility from diseases, such as cancer and its treatment protocols, including radiation and chemo-therapy, and the general lifestyle trend to later marriages. The use of assisted reproductive techniques (ART) in preserving fertility have benefitted significantly from new scientific approaches, such as cryostorage, in which live cells and tissues are stored at low temperatures and revived when necessary. This review focuses on "cryopreservation science monitoring in reproductive biomedicine" to evaluate knowledge, trends, driving forces, impetus, and emerging technologies in order to draw a future roadmap for this field. Our analysis of the field of cryobiology emphasizes the significance of strategic planning of cryobiology research to support more its extensive use in therapeutics in the future. The Royan Institute (Tehran, Iran) recognises this need and has developed a strategic plan to engage in multidisciplinary research on the application of cryobiology, including cryobioengineering, in disease mitigation. We hoped that this study can help improve the quality and quantity of public discourse and expert awareness of the role for cryopreservation in fertility preservation within ART. DOI: 10.54680/fr23410110112.
几十年来，冷冻保存一直被用于保存有活力的生物标本。随着诸如癌症及其治疗方案（包括放疗和化疗）等疾病给人类生育能力带来的风险增加，以及晚婚这一普遍的生活方式趋势，冷冻保存扩展到生育力保存领域成为了自然的结果。在生育力保存中使用辅助生殖技术（ART）显著受益于新的科学方法，比如低温储存，即活细胞和组织在低温下储存，并在必要时复苏。本综述聚焦于“生殖生物医学中的冷冻保存科学监测”，以评估相关知识、趋势、驱动力、推动力和新兴技术，从而为该领域绘制未来路线图。我们对低温生物学领域的分析强调了低温生物学研究战略规划的重要性，以便在未来更广泛地支持其在治疗中的应用。罗扬研究所（伊朗德黑兰）认识到这一需求，并制定了一项战略计划，开展关于低温生物学应用的多学科研究，包括低温生物工程，以减轻疾病。我们希望这项研究有助于提高公众讨论的质量和数量，以及专家对冷冻保存在辅助生殖技术中的生育力保存作用的认识。DOI: https://doi.org/1%200.54680/fr23410110112 （原文DOI链接有误，正确的DOI链接应该是https://doi.org/10.54680/fr23410110112 ，这里按照正确的链接翻译）
