From the Department of Nuclear Medicine, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
Clin Nucl Med. 2024 Jan 1;49(1):e19-e21. doi: 10.1097/RLU.0000000000004941. Epub 2023 Oct 25.
Superscan on PET/CT has been reported in the literature and mainly involved metastatic diseases. We report an uncommon case of a metabolic superscan on 18 F-FDG PET/CT in a 56-year-old man with end-stage renal disease on hemodialysis who presented with secondary hyperparathyroidism. Parathyroid scintigraphy showed 2 lesions posteroinferior to both thyroid lobes, suggestive of parathyroid adenoma/hyperplasia. FDG PET/CT performed to assess for pulmonary nodules revealed diffuse FDG hypermetabolism involving the visualized skull, mandible, spine, sternum, ribs, and appendicular skeleton without corresponding CT lesion with no urinary radiotracer excretion, consistent with metabolic superscan secondary to renal osteodystrophy.
文献中报道过 PET/CT 全身显像过度，主要与转移性病相关。我们报告一例罕见的 18 F-FDG PET/CT 代谢全身显像过度病例，患者为 56 岁男性，终末期肾病行血液透析，伴发甲状旁腺功能亢进。甲状旁腺闪烁显像显示甲状腺两叶后下方有 2 个病灶，提示甲状旁腺腺瘤/增生。行 FDG PET/CT 以评估肺结节，发现包括颅骨、下颌骨、脊柱、胸骨、肋骨和四肢骨骼在内的全身多处 FDG 代谢增高，而相应 CT 无病灶，无尿放射性示踪剂排泄，与继发于肾性骨营养不良的代谢全身显像过度一致。
