Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
PLoS One. 2023 Oct 26;18(10):e0293066. doi: 10.1371/journal.pone.0293066. eCollection 2023.
To assess public awareness, interest, and concerns regarding Vuity (1.25% pilocarpine hydrochloride ophthalmic solution), an eye drop for the treatment of presbyopia, based on Google Trends.
We used Google Trends that provides a relative search volume for queried terms, to evaluate searches for Vuity from June 30, 2021, to June 30, 2022, in the United States. The data for this study were downloaded on June 30, 2022. Main outcome measures were changes in relative search volumes for the terms "Vuity," "Eye drops for reading," "Eye drops for near vision," "Presbyopia," "Pilocarpine," and related popular search terms, such as "Vuity side effects," and "Vuity retinal detachment".
Since the approval of Vuity on October 29, 2021, notable increases in the relative search volumes occurred for Vuity in October 2021, December 2021, and from March to April 2022, which coincided with its approval, availability, and subsequent direct-to-consumer advertising based on positive results of clinical trials. The direct-to-consumer advertising had the greatest impact on the search volume for Vuity. Specific interests included Vuity cost, where to buy it, and its side effects. Retinal detachment was the most highly searched Vuity side effect. Geographic variation was evident, with the relative search volumes highest for "Vuity" in Wyoming, followed by North Dakota.
Google Trends is a useful tool for monitoring increases in public interest in Vuity for presbyopia. Public concerns regarding side effects warrant further real-world investigations of the causal relationship between Vuity and retinal detachment.
基于谷歌趋势评估公众对用于治疗老视的滴眼剂 Vuity(1.25%盐酸毛果芸香碱)的认知、兴趣和关注。
我们使用谷歌趋势,该工具提供查询词的相对搜索量,以评估 2021 年 6 月 30 日至 2022 年 6 月 30 日期间美国对 Vuity 的搜索情况。本研究的数据于 2022 年 6 月 30 日下载。主要观察指标是术语“Vuity”、“阅读用滴眼剂”、“近用滴眼剂”、“老视”、“毛果芸香碱”以及相关热门搜索词(如“Vuity 副作用”和“Vuity 视网膜脱离”)的相对搜索量变化。
自 2021 年 10 月 29 日批准 Vuity 以来,2021 年 10 月、12 月和 2022 年 3 月至 4 月期间,Vuity 的相对搜索量显著增加,这与临床试验的积极结果相关,Vuity 的获批、上市以及随后的直接面向消费者的广告宣传相吻合。直接面向消费者的广告宣传对 Vuity 的搜索量影响最大。具体兴趣包括 Vuity 的成本、购买地点及其副作用。视网膜脱离是 Vuity 最受关注的副作用。地域差异明显,怀俄明州和北达科他州对“Vuity”的相对搜索量最高。
谷歌趋势是监测公众对用于治疗老视的滴眼剂 Vuity 的兴趣增加的有用工具。公众对副作用的担忧需要进一步进行真实世界研究,以调查 Vuity 与视网膜脱离之间的因果关系。