铜标记的放射性示踪剂：替代品还是选择？ - Suppr

Cu-Labeled Radiotracers: Alternative or Choice?

作者信息

Fani Melpomeni, Nicolas Guillaume P

机构信息

Division of Radiopharmaceutical Chemistry, University Hospital Basel, Basel, Switzerland; and

Division of Nuclear Medicine, University Hospital Basel, Basel, Switzerland.

出版信息

J Nucl Med. 2023 Dec 1;64(12):1855-1857. doi: 10.2967/jnumed.123.266171.

DOI:10.2967/jnumed.123.266171

PMID:37884329

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10690116/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b729/10690116/959a91792e2d/jnumed.123.266171f1.jpg

相似文献

Cu-Labeled Radiotracers: Alternative or Choice?

J Nucl Med. 2023 Dec 1;64(12):1855-1857. doi: 10.2967/jnumed.123.266171.

Comparison of image quality with 62Cu and 64Cu-labeled radiotracers in positron emission tomography whole-body phantom imaging.

Hell J Nucl Med. 2015 May-Aug;18(2):103-7. doi: 10.1967/s002449910203. Epub 2015 Jul 20.

Recent advances in copper radiopharmaceuticals.

Curr Radiopharm. 2011 Apr;4(2):109-21. doi: 10.2174/1874471011104020109.

Intrinsically copper-64-labeled organic nanoparticles as radiotracers.

Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13128-31. doi: 10.1002/anie.201206939. Epub 2012 Nov 14.

Derivatization of (±) dihydrotetrabenazine for copper-64 labeling towards long-lived radiotracers for PET imaging of the vesicular monoamine transporter 2.

Bioorg Med Chem Lett. 2014 Dec 15;24(24):5663-5665. doi: 10.1016/j.bmcl.2014.10.070. Epub 2014 Oct 28.

The development of copper radiopharmaceuticals for imaging and therapy.

Med Chem. 2011 Sep;7(5):413-29. doi: 10.2174/157340611796799177.

Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies.

Appl Radiat Isot. 2010 Jan;68(1):5-13. doi: 10.1016/j.apradiso.2009.08.010. Epub 2009 Aug 25.

Three-dimensional maximum a posteriori (MAP) imaging with radiopharmaceuticals labeled with three Cu radionuclides.

Nucl Med Biol. 2006 Feb;33(2):217-26. doi: 10.1016/j.nucmedbio.2005.11.001.

Synthesis and Evaluation of New Generation Cross-Bridged Bifunctional Chelator for (64)Cu Radiotracers.

Inorg Chem. 2015 Sep 8;54(17):8177-86. doi: 10.1021/acs.inorgchem.5b01386. Epub 2015 Aug 19.

Evaluation of 64Cu-labeled bifunctional chelate-bombesin conjugates.

Bioconjug Chem. 2011 Aug 17;22(8):1729-35. doi: 10.1021/bc2002665. Epub 2011 Jul 29.

引用本文的文献

Enhanced contrast in FAP-targeting PET imaging with Cu-labeled FAP inhibitors: development and preclinical evaluation of novel [Cu]Cu-Kalios PET radioligands.

EJNMMI Radiopharm Chem. 2025 Aug 21;10(1):55. doi: 10.1186/s41181-025-00381-4.

Evaluation of Copper-61-Labeled Prostate-specific Membrane Antigen Targeting Novel Radiopharmaceutical: First Steps toward Clinical Implementation.

ACS Pharmacol Transl Sci. 2025 Jun 3;8(6):1580-1590. doi: 10.1021/acsptsci.4c00685. eCollection 2025 Jun 13.

First-in-human administration of [Cu]Cu-NODAGA-LM3 and head-to-head comparison with [Ga]Ga-DOTA-TOC PET/CT as part of the phase I/II COPPER PET in NET study.

Eur J Nucl Med Mol Imaging. 2025 May 24. doi: 10.1007/s00259-025-07301-3.

Is Copper-61 the New Gallium-68? Automation and Preclinical Proof-of-Concept of Cu-Based Radiopharmaceuticals for Prostate Cancer Imaging.

Pharmaceuticals (Basel). 2025 Mar 26;18(4):469. doi: 10.3390/ph18040469.

Unveiling the potential of copper-61 vs. gallium-68 for SSTR PET imaging.

Eur J Nucl Med Mol Imaging. 2025 Jun;52(7):2671-2684. doi: 10.1007/s00259-025-07116-2. Epub 2025 Feb 6.

Radiocopper in Radiopharmacy and Medical Use: Current Status and Perspective.

J Med Chem. 2025 Feb 13;68(3):2356-2376. doi: 10.1021/acs.jmedchem.4c02885. Epub 2025 Feb 2.

Comparative analysis of positron emitters for theranostic applications based on small bioconjugates highlighting Sc, Cu and Ti.

EJNMMI Phys. 2024 Nov 22;11(1):98. doi: 10.1186/s40658-024-00699-z.

Copper-61 is an advantageous alternative to gallium-68 for PET imaging of somatostatin receptor-expressing tumors: a head-to-head comparative preclinical study.

Front Nucl Med. 2024 Oct 11;4:1481343. doi: 10.3389/fnume.2024.1481343. eCollection 2024.

Cu-PSMA-Targeted PET for Prostate Cancer: From Radiotracer Development to First-in-Human Imaging.

J Nucl Med. 2024 Sep 3;65(9):1427-1434. doi: 10.2967/jnumed.123.267126.

本文引用的文献

SNMMI Procedure Standard/EANM Practice Guideline for SSTR PET: Imaging Neuroendocrine Tumors.

J Nucl Med. 2023 Feb;64(2):204-210. doi: 10.2967/jnumed.122.264860.

PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0.

Eur J Nucl Med Mol Imaging. 2023 Apr;50(5):1466-1486. doi: 10.1007/s00259-022-06089-w. Epub 2023 Jan 5.

Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets.

Pharmaceuticals (Basel). 2022 Jun 7;15(6):723. doi: 10.3390/ph15060723.

Radiotheranostics in oncology: current challenges and emerging opportunities.

Nat Rev Clin Oncol. 2022 Aug;19(8):534-550. doi: 10.1038/s41571-022-00652-y. Epub 2022 Jun 20.

Choice Is Good at Times: The Emergence of [Cu]Cu-DOTATATE-Based Somatostatin Receptor Imaging in the Era of [Ga]Ga-DOTATATE.

J Nucl Med. 2022 Sep;63(9):1300-1301. doi: 10.2967/jnumed.122.264183. Epub 2022 May 26.

Automated, cassette-based isolation and formulation of high-purity [Cu]CuCl from solid Ni targets.

EJNMMI Radiopharm Chem. 2020 Nov 5;5(1):21. doi: 10.1186/s41181-020-00108-7.

The Clinical Impact of Additional Late PET/CT Imaging with Ga-PSMA-11 (HBED-CC) in the Diagnosis of Prostate Cancer.

J Nucl Med. 2017 May;58(5):750-755. doi: 10.2967/jnumed.116.183483. Epub 2017 Jan 6.

Glucagon-Like Peptide-1 Receptor PET/CT with 68Ga-NOTA-Exendin-4 for Detecting Localized Insulinoma: A Prospective Cohort Study.

J Nucl Med. 2016 May;57(5):715-20. doi: 10.2967/jnumed.115.167445. Epub 2016 Jan 21.

Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study.

Lancet Diabetes Endocrinol. 2013 Oct;1(2):115-22. doi: 10.1016/S2213-8587(13)70049-4. Epub 2013 Jul 25.

Matching chelators to radiometals for radiopharmaceuticals.

Chem Soc Rev. 2014 Jan 7;43(1):260-90. doi: 10.1039/c3cs60304k. Epub 2013 Oct 30.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Cu-Labeled Radiotracers: Alternative or Choice?

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献