Effect of dehydration on the glomerular granular cells in new-born rat kidney.

A light microscopical study was done to demonstrate the effect of dehydration on the glomerular granular cells in the neonatal rat renal corpuscles. Sprague-Dawley gravid albino rats were used. Their neonates were given nothing per mouth for the first 24 h following birth and used thereafter. Semithin, toluidine blue stained sections of Araldite-embedded tissue were studied. Granular cell index (GCI) was calculated for the glomerular granular cells. The GCI was high in the experimental animals and the granules of the glomerular granular cells increased in number and size. It is suggested that the glomerular granular cells are affected by dehydration.