Cecchi Ryan J, McHugh Jonathan B, Abdulfatah Eman, Lew Madelyn
Department of Pathology, University of Michigan Health System, Ann Arbor, MI, USA.
Urol Case Rep. 2023 Oct 13;51:102583. doi: 10.1016/j.eucr.2023.102583. eCollection 2023 Nov.
Ganglioneuromas are benign tumors arising from the neural crest. Histologically, they are composed of mature Schwann cells and ganglion cells admixed with fibrous tissue. While they frequently are seen in the abdomen and mediastinum, rare reports have highlighted their occurrences in the genitourinary system. The only prior reported prostatic ganglioneuroma arose in a patient with a history of neurofibromatosis type 1. In this report, we highlight the first reported prostatic ganglioneuroma without a known genetic linkage.
神经节神经瘤是起源于神经嵴的良性肿瘤。从组织学上看，它们由成熟的雪旺细胞和神经节细胞与纤维组织混合组成。虽然它们常见于腹部和纵隔，但罕见报道强调了它们在泌尿生殖系统中的发生情况。之前唯一报道的前列腺神经节神经瘤发生在一名患有1型神经纤维瘤病的患者身上。在本报告中，我们重点介绍了首例报道的无已知遗传关联的前列腺神经节神经瘤。
