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成人血流感染患者从急诊科出院后早期口服门诊治疗的安全性。

Safety of early oral ambulatory treatment of adult patients with bloodstream infections discharged from the emergency department.

机构信息

Unit of Infectious Diseases, Microbiology and Parasitology, Virgen del Rocío University Hospital , Seville, Spain.

Institute of Biomedicine of Seville (IBiS), Virgen del Rocío University Hospital/CSIC/University of Seville , Seville, Spain.

出版信息

Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0078023. doi: 10.1128/aac.00780-23. Epub 2023 Oct 27.

DOI:10.1128/aac.00780-23
PMID:37889016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10648851/
Abstract

This study evaluates the safety of early oral ambulatory treatment of adult patients diagnosed with bacteremia after their discharge from the emergency department. A cohort of 206 febrile ambulatory patients was assessed. Bacteremic low-risk patients were recommended an oral treatment and were compared with matched febrile non-bacteremic outpatients. Rates of 14-day mortality and unplanned re-consultations were similar and below 5% in both cohorts, highlighting the safety of oral therapy of low-risk bacteremia, even from its onset.

摘要

本研究评估了对因菌血症从急诊出院的成年患者进行早期口服门诊治疗的安全性。评估了 206 名发热门诊患者。低危菌血症患者被建议接受口服治疗，并与匹配的发热非菌血症门诊患者进行比较。两组患者 14 天死亡率和非计划复诊率相似，均低于 5%，这突出表明低危菌血症的口服治疗甚至在发病早期也是安全的。