Indiana University School of Medicine, Indianapolis, IN.
Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, RI.
R I Med J (2013). 2023 Nov 1;106(10):51-53.
Subcorneal pustular dermatosis (SPD), also called Sneddon-Wilkinson disease, is a rare, relapsing pustular dermatosis.1 SPD has been associated with multiple myeloma, IgA Gammopathy, pyoderma gangrenosum and certain autoimmune diseases.2 However, SPD occurrence following SARS-COV-2 has not yet been reported. Herein, we report a case of SPD occurring after SARS-CoV-2 infection in a 52-year-old male. We hypothesize that the occurrence of SPD shortly following SARS-CoV-2 infection suggests the viral illness may have precipitated onset of SPD, and the patient may remain at risk for future flares of disease despite appropriate treatment and current remission status.
黏膜下脓疱性皮病(SPD),也称斯奈德-威尔金森病,是一种罕见的复发性脓疱性皮肤病。1 SPD 与多发性骨髓瘤、IgA 血症、坏疽性脓皮病和某些自身免疫性疾病有关。2 然而,目前尚未有报道称 SPD 发生在 SARS-COV-2 之后。在此,我们报告一例 52 岁男性 SARS-CoV-2 感染后发生 SPD 的病例。我们推测,SARS-CoV-2 感染后不久发生 SPD 提示病毒感染可能促使 SPD 发病,尽管进行了适当的治疗和目前处于缓解状态,患者仍有发生疾病复发的风险。