Statewide Program for Infection Control and Epidemiology, University of North Carolina (UNC) School of Medicine, Chapel Hill, NC; Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC.
Statewide Program for Infection Control and Epidemiology, University of North Carolina (UNC) School of Medicine, Chapel Hill, NC; Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC; Infection Prevention, University of North Carolina Medical Center, Chapel Hill, NC.
Am J Infect Control. 2023 Nov;51(11S):A72-A81. doi: 10.1016/j.ajic.2023.01.019.
There are several sources of pathogens that cause surgical site infections (SSI) to include the patients endogenous microflora and exogenous sources (e.g., air, surfaces, staff, surgical equipment).
We searched the published English literature (Google, Google Scholar, PubMed) for articles on reprocessing surgical instruments, effectiveness of sterilization methods, microbial load on surgical instruments, frequency of "contaminated" instruments, and the infection risk associated with "contaminated" surgical instruments and immediate use steam sterilization.
There is substantial redundancy in instrument reprocessing to include: even if a patient was exposed to a "contaminated" instrument, the decontamination and sterilization process would have removed and/or inactivated the contaminating pathogens due to the exceptional effectiveness of the manual and mechanical cleaning (i.e., washer-disinfector) and the remarkable robustness of sterilization technology; and the low-level of microorganisms on surgical instruments after use and before cleaning.
A critical review of the literature suggests that the risk of acquiring an SSI from instruments used in surgery is essentially zero if the sterilization cycle is validated.
导致手术部位感染(SSI)的病原体有几个来源,包括患者的内源性微生物群和外源性来源(例如,空气、表面、工作人员、手术设备)。
我们在已发表的英文文献(Google、Google Scholar、PubMed)中搜索了有关手术器械再处理、消毒方法效果、手术器械上微生物负荷、“污染”器械的频率以及与“污染”手术器械和立即使用蒸汽灭菌相关的感染风险的文章。
器械再处理存在大量重复,包括:即使患者接触到“污染”器械,由于手动和机械清洗(即清洗消毒器)的极高效率和消毒技术的卓越稳健性,去污和消毒过程也会去除和/或灭活污染病原体;以及使用后和清洁前手术器械上微生物的低水平。
对文献的批判性回顾表明,如果消毒循环经过验证,那么从手术中使用的器械中获得 SSI 的风险基本上为零。