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关于近期社区水氟化研究的评论。

Comments on recent community water fluoridation studies.

机构信息

UK National Community Water Fluoridation Network, Leeds, UK.

British Fluoridation Society, Oldham, UK.

出版信息

Br Dent J. 2023 Oct;235(8):639-641. doi: 10.1038/s41415-023-6338-z. Epub 2023 Oct 27.

Abstract

Water fluoridation is a public health measure to reduce levels of dental caries in populations. A report of the recently completed CATFISH study has been published. This was the first UK evaluation of fluoridation introduction for many years; it was carefully designed and executed and is welcomed. The purpose of this article is to highlight the 180-page report of the study and comment on some aspects to aid interpretation of the findings. Significant features were that two cohorts, from birth and from five years, were followed for six years in a fluoridated and a non-fluoridated area, and clinical and cost analyses were reported. Areas of the report which deserve comment are: a) interruption of fluoridation for a year for half the children in the intervention area and its effect; b) clinical results were reported as absolute reduction in caries prevalence, with the preventive fraction for caries severity downplayed; c) the power of the study was diminished by an unexpected lower caries increment; and d) control for differences in diet was not possible. Nevertheless, this major UK study showed clinical and cost benefits of water fluoridation. The risk of cessation of water fluoridation is highlighted in examples of three recently published studies.

摘要

水氟化是一种公共卫生措施,旨在降低人群的龋齿水平。最近完成的 CATFISH 研究报告已经发布。这是多年来英国首次对氟化引入进行评估;该研究经过精心设计和实施,受到欢迎。本文的目的是突出该研究的 180 页报告,并对某些方面进行评论,以帮助解释研究结果。显著特点是,在氟化和非氟化地区,两个队列(出生队列和五岁队列)分别进行了六年的随访,同时报告了临床和成本分析。报告中值得评论的领域包括:a)干预地区一半儿童的氟化中断一年及其影响;b)临床结果以龋齿流行率的绝对减少报告,对龋齿严重程度的预防分数轻描淡写;c)由于意外的龋齿增量较低,研究的效力降低;d)不可能进行饮食差异的对照。尽管如此,这项英国主要研究表明水氟化具有临床和成本效益。最近发表的三项研究的例子突出了停止水氟化的风险。

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