Tsolakopoulos Dimitrios, Kasselimis Dimitrios, Laskaris Nikolaos, Angelopoulou Georgia, Papageorgiou Georgios, Velonakis Georgios, Varkanitsa Maria, Tountopoulou Argyro, Vassilopoulou Sofia, Goutsos Dionysis, Potagas Constantin
Neuropsychology and Language Disorders Unit, 1st Department of Neurology, Eginition Hospital, National and Kapodistrian University of Athens, 72-74 Vas. Sofias Av., 11528 Athens, Greece.
Department of Psychology, Panteion University of Social and Political Sciences, 17671 Athens, Greece.
Brain Sci. 2023 Sep 29;13(10):1385. doi: 10.3390/brainsci13101385.
Research investigating pragmatic deficits in individuals with right hemisphere damage focuses on identifying the potential mechanisms responsible for the nature of these impairments. Nonetheless, the presumed shared cognitive mechanisms that could account for these deficits have not yet been established through data-based evidence from lesion studies. This study aimed to examine the co-occurrence of pragmatic language deficits, Theory of Mind impairments, and executive functions while also exploring their associations with brain lesion sites. Twenty-five patients suffering from unilateral right hemisphere stroke and thirty-seven healthy participants were recruited for this study. The two groups were tested in pragmatics, Theory of Mind, and executive function tasks. Structural imaging data were also obtained for the identification of the lesion sites. The findings of this study suggest a potential convergence among the three aforementioned cognitive mechanisms. Moreover, we postulate a hypothesis for a neural circuitry for communication impairments observed in individuals with right hemisphere damage.
针对右半球损伤个体语用缺陷的研究，聚焦于确定导致这些损伤性质的潜在机制。然而，那些可能解释这些缺陷的假定共享认知机制，尚未通过基于损伤研究的实证证据得以确立。本研究旨在考察语用语言缺陷、心理理论损伤和执行功能的共现情况，同时探究它们与脑损伤部位的关联。本研究招募了25名单侧右半球中风患者和37名健康参与者。两组参与者接受了语用学、心理理论和执行功能任务测试。还获取了结构成像数据以确定损伤部位。本研究结果表明上述三种认知机制之间可能存在趋同现象。此外，我们针对右半球损伤个体中观察到的沟通障碍提出了一种神经回路假说。
