Stephens Jaclyn A, Press Denny, Atkins Jennifer, Duffy John R, Thomas Michael L, Weaver Jennifer A, Schmid Arlene A
Department of Occupational Therapy, Colorado State University, Fort Collins, CO 80524, USA.
Molecular, Cellular and Integrative Neuroscience Program, Colorado State University, Fort Collins, CO 80521, USA.
Brain Sci. 2023 Oct 5;13(10):1413. doi: 10.3390/brainsci13101413.
To date, no one has prospectively evaluated yoga intervention-induced changes in brain structure or function in adults with acquired brain injuries (ABI). Thus, this study was conducted to test the feasibility of acquiring neuroimaging data from adults with ABI before and after a yoga intervention.
This was a single-arm intervention feasibility study that included 12 adults with chronic (i.e., greater than 6 months post-injury) ABI and self-reported limitations in balance. Neuroimaging data were acquired before and after yoga. The yoga intervention was completed once per week for eight weeks. Feasibility objectives and benchmarks were established a priori.
Most feasibility objectives and benchmarks were achieved. The goal of recruiting 12 participants was successfully achieved, and 75% of participants were retained throughout the study (goal of 80%). All imaging feasibility benchmarks were met; rs-fMRI and fNIRS data were acquired safely, data were of acceptable quality, and data pre-processing procedures were successful. Additionally, improvements were detected in balance after yoga, as group-level balance was significantly better post-yoga compared to pre-yoga, = 0.043.
These findings indicate it is feasible to acquire neuroimaging data from adults with ABI before and after a yoga intervention. Thus, future prospective studies are warranted.
迄今为止，尚无研究对后天性脑损伤（ABI）成人进行前瞻性评估瑜伽干预对大脑结构或功能的影响。因此，本研究旨在测试在瑜伽干预前后获取ABI成人神经影像数据的可行性。
这是一项单臂干预可行性研究，纳入了12名患有慢性（即受伤后超过6个月）ABI且自我报告存在平衡功能受限的成年人。在瑜伽干预前后获取神经影像数据。瑜伽干预每周进行一次，共持续八周。可行性目标和基准是预先设定的。
大多数可行性目标和基准均已达成。成功招募到12名参与者的目标得以实现，且在整个研究过程中75%的参与者被保留（目标为80%）。所有成像可行性基准均得到满足；静息态功能磁共振成像（rs-fMRI）和功能性近红外光谱（fNIRS）数据安全获取，数据质量可接受，且数据预处理程序成功完成。此外，瑜伽后平衡功能有所改善，因为与瑜伽前相比，瑜伽后组水平的平衡功能显著更好，P = 0.043。
这些研究结果表明，在瑜伽干预前后获取ABI成人的神经影像数据是可行的。因此，未来有必要开展前瞻性研究。
