Clinical Division of Traumatology, Department of Orthopedics and Trauma Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Clinical Division of Orthopedics, Department of Orthopedics and Trauma Surgery, Medical University of Vienna, 1090 Vienna, Austria.
Nutrients. 2023 Oct 14;15(20):4367. doi: 10.3390/nu15204367.
Patients aged 65 and over who are accommodated in hospitals and nursing homes are at high risk of malnutrition and often show signs of it. The future relevance of this problem becomes clear, especially in view of the demographic development of the coming years and decades. In this study, the correlation between malnutrition, hypoalbuminemia, anemia, elevated CRP, and low transferrin levels, as well as mortality in seniors between 65 and 100 years, should be revealed. Therefore, the prevalence of disease-specific malnutrition (DRM), according to the criteria of the guidelines of the German Society of Nutritional Medicine (DGEM), and the prevalence of hypoalbuminemia were presented based on the data of 120 residents who were inpatients in a large Viennese nursing home between 01/2017 and 08/2020. Moreover, 86 of the inpatient residents were women and 34 were men, with a mean age of 84 years (SD: 8.7). In this examination, more than one-third of nursing home residents were malnourished. More than half of the residents were found to have low serum albumin or low transferrin saturation. However, no correlation between elevated CRP, low transferrin, or low serum albumin values and malnutrition could be established. Residents with low serum albumin or low transferrin levels, however, had a higher mortality rate. This study supports the urgent relevance of closer and individually personalized medical nutritional interventions, especially concerning hypoalbuminemic seniors aged 65 years and older.
65 岁及以上的住院和养老院患者存在营养不良的高风险,且常出现营养不良的迹象。鉴于未来几年和几十年的人口发展情况,该问题的未来相关性变得清晰可见。在这项研究中,应揭示 65 至 100 岁老年人中营养不良、低白蛋白血症、贫血、CRP 升高和转铁蛋白水平降低与死亡率之间的相关性。因此,根据德国营养医学学会(DGEM)指南的标准,呈现了特定疾病相关的营养不良(DRM)的流行情况,并基于 2017 年 1 月至 2020 年 8 月期间在维也纳一家大型养老院住院的 120 名居民的数据呈现了低白蛋白血症的流行情况。此外,86 名住院居民为女性,34 名男性,平均年龄为 84 岁(SD:8.7)。在这项检查中,超过三分之一的养老院居民存在营养不良。超过一半的居民的血清白蛋白或转铁蛋白饱和度较低。然而,并未发现 CRP 升高、转铁蛋白低或低血清白蛋白值与营养不良之间存在相关性。然而,血清白蛋白或转铁蛋白水平较低的居民死亡率更高。这项研究支持更密切和个性化的医学营养干预的紧迫性,特别是对于 65 岁及以上的低白蛋白血症老年人。