Johannesson Liza, Anderson Sophie, Putman J Michael, Gunby Robert T, Zhang Lilly, Testa Giuliano, Gregg Anthony R
Baylor Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX 75246, USA.
Department of Obstetrics and Gynecology, Baylor University Medical Center, Dallas, TX 75246, USA.
J Clin Med. 2023 Oct 11;12(20):6463. doi: 10.3390/jcm12206463.
Recipients of uterus transplantation have unique factors that may increase their risk of cervical insufficiency. This report describes a uterus transplant recipient with cervical insufficiency resulting in two second-trimester miscarriages. After McDonald cerclages (one that failed), she underwent an interval transabdominal cerclage and delivered a healthy term child in her third pregnancy. The longitudinal information of this case provides observations from which we can propose testable hypotheses that address venous outflow and inflammation. This case also suggests that there could be a role for prophylactic cerclage placement at the time of transplantation.
子宫移植受者有一些独特的因素，可能会增加其宫颈机能不全的风险。本报告描述了一名子宫移植受者，她因宫颈机能不全导致两次孕中期流产。在进行了麦克唐纳宫颈环扎术（其中一次失败）后，她接受了经腹间隔宫颈环扎术，并在第三次怀孕时生下了一个健康的足月婴儿。该病例的纵向信息提供了一些观察结果，据此我们可以提出可检验的假设，以探讨静脉流出和炎症问题。该病例还表明，在移植时进行预防性宫颈环扎术可能会有作用。
