Moncho Dulce, Poca Maria A, Rahnama Kimia, Sánchez Roldán M Ángeles, Santa-Cruz Daniela, Sahuquillo Juan
Department of Clinical Neurophysiology, Vall d'Hebron University Hospital, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
Neurotraumatology and Neurosurgery Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.
J Clin Med. 2023 Oct 11;12(20):6472. doi: 10.3390/jcm12206472.
Chiari malformation type 1 (CM1) includes various congenital anomalies that share ectopia of the cerebellar tonsils lower than the foramen magnum, in some cases associated with syringomyelia or hydrocephalus. CM1 can cause dysfunction of the brainstem, spinal cord, and cranial nerves. This functional alteration of the nervous system can be detected by various modalities of neurophysiological tests, such as brainstem auditory evoked potentials, somatosensory evoked potentials, motor evoked potentials, electromyography and nerve conduction studies of the cranial nerves and spinal roots, as well as brainstem reflexes. The main goal of this study is to review the findings of multimodal neurophysiological examinations in published studies of patients with CM1 and their indication in the diagnosis, treatment, and follow-up of these patients, as well as their utility in intraoperative monitoring.
1型Chiari畸形（CM1）包括各种先天性异常，其共同特征是小脑扁桃体异位至枕大孔以下，在某些情况下伴有脊髓空洞症或脑积水。CM1可导致脑干、脊髓和颅神经功能障碍。这种神经系统的功能改变可通过多种神经生理学测试方法检测到，如脑干听觉诱发电位、体感诱发电位、运动诱发电位、肌电图以及颅神经和脊神经根的神经传导研究，还有脑干反射。本研究的主要目的是回顾已发表的关于CM1患者多模态神经生理学检查的结果及其在这些患者的诊断、治疗和随访中的应用，以及它们在术中监测中的效用。
