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拔牙创愈合的当前知识:一项叙述性综述

Current Knowledge on the Healing of the Extraction Socket: A Narrative Review.

作者信息

Udeabor Samuel E, Heselich Anja, Al-Maawi Sarah, Alqahtani Ali F, Sader Robert, Ghanaati Shahram

机构信息

Department of Oral and Maxillofacial Surgery, College of Dentistry, King Khalid University, Abha 62529, Saudi Arabia.

Department of Oral, Cranio-Maxillofacial, and Facial Plastic Surgery & Frankfurt Orofacial Regenerative Medicine (FORM) Lab, Johann Wolfgang Goethe University, 60590 Frankfurt am Main, Germany.

出版信息

Bioengineering (Basel). 2023 Sep 29;10(10):1145. doi: 10.3390/bioengineering10101145.

DOI:10.3390/bioengineering10101145
PMID:37892875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10604628/
Abstract

The concept of extraction socket healing has been severally researched and reported over the years, since tooth extraction remains one of the most common procedures performed in the dental clinic. Understanding this healing process is of utmost importance because the outcome has a direct bearing on future prosthetic rehabilitation and, by extension, on patients' esthetics and masticatory function, among others. This mini review, therefore, summarized the current knowledge on the different stages of socket healing, including the biologic and clinical events that occur following tooth extraction up until the complete closure of the socket. Additionally, the modeling of the alveolar bone/process post extraction, and the resultant dimensional changes that, altogether, shape the bone, were reviewed and documented. The effects of various socket preservation interventions to mitigate these dimensional changes, and therefore preserve the alveolar process in a condition suitable for future prosthetic rehabilitation, were highlighted. Finally, a review of some of the factors that influence the entire process was also carried out.

摘要

多年来,拔牙创愈合的概念已得到多次研究和报道,因为拔牙仍是牙科诊所最常见的操作之一。了解这一愈合过程至关重要,因为其结果直接关系到未来的修复重建,进而影响患者的美观和咀嚼功能等。因此,本综述总结了目前关于拔牙创愈合不同阶段的知识,包括拔牙后直至拔牙创完全封闭所发生的生物学和临床事件。此外,还对拔牙后牙槽骨/牙槽突的重塑以及由此导致的影响骨形态的尺寸变化进行了综述和记录。强调了各种拔牙创保存干预措施对减轻这些尺寸变化的作用,从而使牙槽突保持在适合未来修复重建的状态。最后,还对一些影响整个过程的因素进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ee/10604628/701263f1480e/bioengineering-10-01145-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ee/10604628/a7b1a1a4fa0e/bioengineering-10-01145-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ee/10604628/701263f1480e/bioengineering-10-01145-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ee/10604628/a7b1a1a4fa0e/bioengineering-10-01145-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ee/10604628/701263f1480e/bioengineering-10-01145-g001.jpg

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2
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BMC Oral Health. 2023 Apr 19;23(1):226. doi: 10.1186/s12903-023-02930-2.
3
Denervation delays initial bone healing of rat tooth extraction socket.
Collagen-Based Products in Wound, Skin, and Health Care.
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Adv Wound Care (New Rochelle). 2025 Jul 28. doi: 10.1177/21621918251361118.
4
Synthesis, physical characteristics, and biocompatibility test of chitosan-alginate-fucoidan scaffold as an alternative material for alveolar bone substitution.壳聚糖-海藻酸盐-岩藻依聚糖支架作为牙槽骨替代材料的合成、物理特性及生物相容性测试
BMC Oral Health. 2025 Jul 18;25(1):1199. doi: 10.1186/s12903-025-06591-1.
5
Evaluation of the Effectiveness of the Socket Preservation Technique Using Allogeneic and Xenogeneic Materials-A Preliminary Study.使用同种异体和异种材料的牙槽窝保存技术有效性评估——一项初步研究。
J Funct Biomater. 2025 May 23;16(6):192. doi: 10.3390/jfb16060192.
6
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7
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