Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 41345 Gothenburg, Sweden.
Department of Surgery, Sahlgrenska University Hospital, Region Västra Götaland, 41345 Gothenburg, Sweden.
Medicina (Kaunas). 2023 Sep 27;59(10):1727. doi: 10.3390/medicina59101727.
The magnetic technique using superparamagnetic nanoparticles of iron oxide has been well established for sentinel lymph node detection. Its main advantage is in the context of logistics, with the possibility to inject several weeks before surgery and the possibility to give access to sentinel lymph node biopsy for women worldwide in places without nuclear medicine facilities. We have not yet seen the full potential of this technique, and new implications have been developed for breast tumour localisation with paramagnetic clips and axillary staging after neoadjuvant chemotherapy using paramagnetic clips inserted in lymph node metastases before chemotherapy. In this report, we have presented our experience of the magnetic technique starting in 2014, and we have highlighted our current and future research directions.
磁性技术使用超顺磁性氧化铁纳米颗粒已被广泛应用于前哨淋巴结检测。其主要优点在于物流方面，可在术前数周内注射，并可使全球范围内无核医学设备的地方的女性都能进行前哨淋巴结活检。我们尚未看到该技术的全部潜力，新的应用包括使用顺磁夹进行乳腺癌肿瘤定位，以及在前化疗时在淋巴结转移部位插入顺磁夹进行新辅助化疗后的腋窝分期。在本报告中，我们介绍了自 2014 年开始使用磁性技术的经验，并强调了我们当前和未来的研究方向。
