Bauer G
Anaesthesist. 1986 Oct;35(10):628-33.
A 51 year old woman patient with undiagnosed hypertension and established diabetes mellitus was to undergo hysterectomy. The induced neurolept-analgesia was interrupted because of sudden increase in the heart rate. Plasma adrenaline and noradrenaline values showed an approximately 12-fold increase. With signs of an extreme peripheral vasoconstriction, the patient died about 11 h after the start of anaesthesia. The post-mortem revealed an apricotsized, hormonally active pheochromocytoma of the left suprarenal body. Following investigation of the pathophysiological and pharmacological process, the case is analyzed from the medico-legal view, the non-clarification of the hypertension as objective failure to exercise due care is put up for discussion, and the question of causality and imputation discussed. Anesthesia in the presence of an undetected pheochromocytoma may be so rare that the criterion of adequacy, i.e. the objective predictability, cannot be applied. None the less the case demonstrates once again the physician's special duty to exercise due care. A precondition for any responsible choice of therapy must be accurate and comprehensive compilation of the findings.
一名51岁患有未确诊高血压和已确诊糖尿病的女性患者准备接受子宫切除术。由于心率突然升高,诱导性神经安定镇痛被中断。血浆肾上腺素和去甲肾上腺素值显示增加了约12倍。患者出现极度外周血管收缩的体征,在麻醉开始约11小时后死亡。尸检发现左肾上腺有一个杏子大小、具有激素活性的嗜铬细胞瘤。在对病理生理和药理过程进行研究后,从法医学角度对该病例进行了分析,讨论了未明确高血压作为客观上未尽注意义务的情况,并探讨了因果关系和归责问题。在存在未被发现的嗜铬细胞瘤的情况下进行麻醉可能非常罕见,以至于充分性标准,即客观可预测性,无法适用。尽管如此,该病例再次证明了医生负有特别的注意义务。任何负责任的治疗选择的前提必须是准确和全面地汇总检查结果。