小细胞山羊携带红细胞的特性：其制备及体内存活情况
Properties of microcytic caprine carrier red blood cells: their preparation and in vivo survival.
作者信息
DeLoach J R, Droleskey R
出版信息
Am J Vet Res. 1986 Nov;47(11):2368-72.
PMID:3789496
Abstract
Dialysis encapsulation was used to prepare caprine-carrier RBC. Optimal conditions for encapsulation are described in which 23% of added [14C]sucrose was entrapped. Carrier RBC were stable in vitro releasing only 5% of entrapped substance in 24 hour. Injected-carrier RBC circulated with a 47-day half-life. Although markedly smaller in size (10 fl vs 15 fl), caprine-carrier RBC were morphologically identical to normal RBC.
摘要
采用透析包封法制备了山羊载体红细胞。文中描述了包封的最佳条件，在此条件下，所添加的[14C]蔗糖有23%被截留。载体红细胞在体外稳定，24小时内仅释放5%的截留物质。注射后的载体红细胞循环半衰期为47天。尽管山羊载体红细胞的体积明显更小（10飞升对15飞升），但其形态与正常红细胞相同。
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