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初产妇与经产妇且有一次择期剖宫产史的单胎妊娠自然阴道分娩的分娩进程、分娩干预措施及围产期结局:一项回顾性比较研究

Delivery Progress, Labor Interventions and Perinatal Outcome in Spontaneous Vaginal Delivery of Singleton Pregnancies between Nulliparous and Primiparous Women with One Previous Elective Cesarean Section: A Retrospective Comparative Study.

作者信息

Karampas Grigorios, Witkowski Martin, Metallinou Dimitra, Steinwall Margareta, Matsas Alkis, Panoskaltsis Theodoros, Christopoulos Panagiotis

机构信息

Department of Obstetrics and Gynecology, Skånes University Hospital, 21428 Malmö-Lund, Sweden.

Second Department of Obstetrics & Gynecology, Medical School, University of Athens "Aretaieion" Hospital, 11528 Athens, Greece.

出版信息

Life (Basel). 2023 Oct 5;13(10):2016. doi: 10.3390/life13102016.

Abstract

UNLABELLED

Trial of labor after cesarean (TOLAC) is an alternative to repeated cesarean for women with singleton pregnancy and one previous transverse lower segment cesarean section (LSCS), resulting in most cases being a successful vaginal birth after cesarean section (VBAC). The primary objective of this study was to examine if the progress and the duration of the active first stage and the second stage of labor in nulliparous women with singleton pregnancy, spontaneous start of labor and vaginal birth differ from primiparous women succeeding VBAC after one previous elective LSCS in a country with a low cesarean section and high VBAC rate. Secondary objectives were to compare labor interventions and maternal-neonatal outcomes between the two groups.

METHODS

This is a retrospective comparative study. Data were collected in a four-year period at the departments of Obstetrics and Gynecology at Kristianstad and Ystad hospitals in Sweden. Out of 14,925 deliveries, 106 primipara women with one previous elective LSCS and a spontaneous labor onset in the subsequent singleton pregnancy were identified. Of these women, 94 (88.7%) delivered vaginally and were included in the study (VBAC group). The comparison group included 212 randomly selected nulliparous women that had a normal singleton pregnancy, spontaneous labor onset and delivered vaginally.

RESULTS

The rate of cervical dilation during the active first stage of labor as well as the duration of the second stage did not differ between the two groups. When adjusting for cervical dilation at admission, there was no significant difference between the two groups regarding the duration of the active phase of the first stage of labor. No significant differences were found in maternal-neonatal outcomes between the two groups except for higher birth weight in the VBAC group. The use of epidural analgesia was associated with slower dilation rhythm over the duration of the active phase and second stage of labor, need for labor augmentation, postpartum bleeding and need for transfusion at higher rates, irrespective of parity when epidural was used.

CONCLUSIONS

Our study provides evidence that in women with one previous elective LSCS undergoing TOLAC in the subsequent pregnancy resulting in vaginal birth, the progress and duration of labor are not different from those in nulliparous women when labor is spontaneous and the it is a singleton pregnancy. The use of epidural was associated with prolonged labor, need for labor augmentation and higher postpartum bleeding, irrespective of parity. This information may be useful in patient counseling and labor management in TOLAC.

摘要

未标注

对于单胎妊娠且既往有一次子宫下段横切口剖宫产史(LSCS)的女性,剖宫产术后阴道试产(TOLAC)是重复剖宫产的一种替代方案,在大多数情况下可成功实现剖宫产术后阴道分娩(VBAC)。本研究的主要目的是探讨在一个剖宫产率低、VBAC率高的国家,单胎妊娠、自然发动分娩并经阴道分娩的初产妇,其产程进展以及第一产程活跃期和第二产程的持续时间与既往一次选择性LSCS后成功实现VBAC的经产妇是否存在差异。次要目的是比较两组之间的分娩干预措施及母婴结局。

方法

这是一项回顾性比较研究。在瑞典克里斯蒂安斯塔德和耶斯塔德医院的妇产科收集了为期四年的数据。在14925例分娩中,确定了106例既往有一次选择性LSCS且在随后的单胎妊娠中自然发动分娩的初产妇。其中,94例(88.7%)经阴道分娩并纳入研究(VBAC组)。对照组包括212例随机选取的单胎妊娠、自然发动分娩并经阴道分娩的初产妇。

结果

两组在第一产程活跃期的宫颈扩张率以及第二产程的持续时间方面无差异。在调整入院时的宫颈扩张情况后,两组在第一产程活跃期的持续时间方面无显著差异。除VBAC组出生体重较高外,两组在母婴结局方面未发现显著差异。无论产妇孕周如何,使用硬膜外镇痛与活跃期及第二产程期间较慢的扩张节律、需要加强宫缩、产后出血以及更高的输血需求相关。

结论

我们的研究表明,对于既往有一次选择性LSCS且在随后妊娠中经TOLAC实现阴道分娩的女性,当分娩为自然发动且为单胎妊娠时,产程进展和持续时间与初产妇并无不同。无论产妇孕周如何,使用硬膜外镇痛与产程延长、需要加强宫缩以及更高的产后出血风险相关。这些信息可能对TOLAC中的患者咨询和分娩管理有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e15a/10608638/601cbf4cda68/life-13-02016-g001.jpg

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