Khubchandani Jagdish, Banerjee Srikanta, Gonzales-Lagos Rafael, Szirony G Michael
College of Health, Education, and Social Transformation New Mexico State University Las Cruces, NM, 88003, USA.
College of Health SciencesWalden University Minneapolis, MN, 55401, USA.
Diabetes Metab Syndr. 2023 Nov;17(11):102892. doi: 10.1016/j.dsx.2023.102892. Epub 2023 Oct 18.
Type 2 Diabetes (T2D) and depression are leading global public health problems associated with profound disability and lower quality of life. Extensive evidence suggests that the two disorders are frequently comorbid. However, long-term effects such as the risk of mortality due to depression among people living with T2D are not well explored.
Data from the National Health and Nutrition Examination Survey, 2005-2010 were linked with mortality files from the National Death Index up to December 31st, 2019.
A total of 14,920 American adults were included in the study sample; nearly a tenth of them had depression (9.08 %) or T2D (10 %). In adjusted analysis, individuals with T2D were 1.70 times more likely (95 % CI = 1.42-2.03) to die than those without T2D. Among people living with T2D without depression, the risk of mortality was 1.55 times higher, but those with both T2D and depression had a 4.24 times higher risk of mortality.
Given the greater risk of morbidity and premature mortality with cooccurring T2D and depression, widespread screening is warranted with a focus on high-risk groups. Integrated and collaborative care models can help address the psychosocial needs of people with T2D and should be widely implemented with the sensitization of clinicians and care teams in primary and specialist care for T2D.
2型糖尿病（T2D）和抑郁症是全球主要的公共卫生问题，与严重残疾和较低的生活质量相关。大量证据表明，这两种疾病经常同时存在。然而，诸如T2D患者因抑郁症导致的死亡风险等长期影响尚未得到充分研究。
将2005 - 2010年美国国家健康与营养检查调查的数据与截至2019年12月31日的国家死亡指数的死亡率文件相链接。
研究样本共纳入14,920名美国成年人；其中近十分之一患有抑郁症（9.08%）或T2D（10%）。在调整分析中，患有T2D的个体死亡可能性是未患T2D个体的1.70倍（95%置信区间 = 1.42 - 2.03）。在未患抑郁症的T2D患者中，死亡风险高1.55倍，但同时患有T2D和抑郁症的患者死亡风险高4.24倍。
鉴于T2D和抑郁症同时存在会带来更高的发病风险和过早死亡风险，有必要对高危人群进行广泛筛查。综合协作护理模式有助于满足T2D患者的心理社会需求，应在基层和专科护理的临床医生及护理团队对T2D有所认识的情况下广泛实施。
