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腹腔镜耻骨后悬吊固定术与腹腔镜高位骶骨子宫固定术治疗子宫中重度脱垂的近期疗效比较

Comparison of efficacy between laparoscopic pectopexy and laparoscopic high uterosacral ligament suspension in the treatment of apical prolapse-short term results.

机构信息

The Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Zhengzhou Key Laboratory of Endometrial Disease Prevention and Treatment, Zhengzhou, China.

出版信息

Sci Rep. 2023 Oct 28;13(1):18519. doi: 10.1038/s41598-023-45871-0.

DOI:10.1038/s41598-023-45871-0
PMID:37898708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10613309/
Abstract

To compare the clinical efficacy of laparoscopic pectopexy and laparoscopic high uterosacral ligament suspension in women suffering from apical prolapse. The clinical data of 170 patients with apical prolapse (POP-Q score ≥ II) treated in the Third Affiliated Hospital of Zhengzhou University from January 2018 to July 2020 were retrospectively analyzed to assess the clinical efficacy of three surgical methods [laparoscopic pectopexy with uterine preservation, laparoscopic pectopexy with hysterectomy, laparoscopic high uterosacral ligament suspension (LHUSLS) with hysterectomy]. Patients were divided into three groups depending on Surgical methods: laparoscopic uterine pectopexy group (n = 23), laparoscopic pectopexy with hysterectomy group (n = 78) and LHUSLS with hysterectomy group (n = 69). The POP-Q points before and after operation were analyzed. The operation-related indices, perioperative periods and post-operative complications were compared. 1. The operation time of laparoscopic uterine pectopexy group was the shortest (p < 0.05). There was no significant difference in the incidence of apical prolapse and new stress urinary incontinence among the three groups during the follow-up period (p > 0.05). 2. The POP-Q points (Aa, Ba, C) in the three groups were better than those before operation (p < 0.05). Laparoscopic pectopexy with hysterectomy group had better Ap, Bp and C points and a longer TVL than LHUSLS with hysterectomy group (p < 0.05). 3. The postoperative PFDI-20, PFIQ-7 and PISQ-12 scores of the three groups were significantly improved than those before operation (p < 0.05). The PISQ-12 scores in laparoscopic uterine pectopexy group were significantly higher than that in the other two groups one year after operation (p < 0.05). The study concludes that laparoscopic pectopexy and LHUSLS can significantly improve the quality of life and sexual function for patients with apical prolapse. One year after operation, laparoscopic pectopexy has a more satisfactory anatomical reduction than LHUSLS with hysterectomy. The laparoscopic uterine pectopexy group had lower postoperative complications and better sexual function than that with hysterectomy group. Laparoscopic pectopexy should be used for the treatment of apical prolapse (POP-Q score ≥ II) patients who aim to better clinical efficacy and sexual function improvement.

摘要

比较腹腔镜耻骨宫颈悬吊术和腹腔镜高位子宫骶韧带悬吊术治疗女性顶端脱垂的临床疗效。回顾性分析 2018 年 1 月至 2020 年 7 月郑州大学第三附属医院收治的 170 例顶端脱垂患者(POP-Q 评分≥Ⅱ)的临床资料,评估 3 种手术方法的临床疗效[腹腔镜保留子宫耻骨宫颈悬吊术、腹腔镜子宫切除术耻骨宫颈悬吊术、腹腔镜高位子宫骶韧带悬吊术(LHUSLS)伴子宫切除术]。根据手术方法将患者分为三组:腹腔镜子宫耻骨宫颈悬吊术组(n=23)、腹腔镜子宫切除术耻骨宫颈悬吊术组(n=78)和腹腔镜高位子宫骶韧带悬吊术伴子宫切除术组(n=69)。分析手术前后的 POP-Q 点。比较手术相关指标、围手术期及术后并发症。1.腹腔镜子宫耻骨宫颈悬吊术组手术时间最短(p<0.05)。随访期间三组间顶端脱垂和新发压力性尿失禁发生率无统计学差异(p>0.05)。2.三组患者 POP-Q 点(Aa、Ba、C)均优于术前(p<0.05)。腹腔镜子宫切除术耻骨宫颈悬吊术组 Ap、Bp 和 C 点优于腹腔镜高位子宫骶韧带悬吊术伴子宫切除术组,TVL 较长(p<0.05)。3.三组术后 PFDI-20、PFIQ-7 和 PISQ-12 评分均较术前明显改善(p<0.05)。术后 1 年腹腔镜子宫耻骨宫颈悬吊术组 PISQ-12 评分明显高于其他两组(p<0.05)。研究表明,腹腔镜耻骨宫颈悬吊术和 LHUSLS 均可显著改善顶端脱垂患者的生活质量和性功能。术后 1 年,腹腔镜耻骨宫颈悬吊术的解剖复位效果优于腹腔镜高位子宫骶韧带悬吊术伴子宫切除术。腹腔镜子宫耻骨宫颈悬吊术组术后并发症发生率较低,性功能优于子宫切除术组。腹腔镜耻骨宫颈悬吊术应作为治疗顶端脱垂(POP-Q 评分≥Ⅱ)患者的首选,以获得更好的临床疗效和性功能改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/2e192d28a2e3/41598_2023_45871_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/67fb78c066e8/41598_2023_45871_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/92d399803a4a/41598_2023_45871_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/2e192d28a2e3/41598_2023_45871_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/67fb78c066e8/41598_2023_45871_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/92d399803a4a/41598_2023_45871_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10613309/2e192d28a2e3/41598_2023_45871_Fig3_HTML.jpg

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使用PISQ-IR问卷比较腹腔镜侧方悬吊术与腹腔镜骶骨宫颈固定术之间的性功能。
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