Department of Abdominal Surgery, University Hospitals Leuven, Herestraat 49, 3000, Louvain, KU, Belgium.
Updates Surg. 2024 Jan;76(1):309-313. doi: 10.1007/s13304-023-01673-7. Epub 2023 Oct 29.
Anal squamous cell carcinoma (ASCC) is the most common histological subtype of malignant tumor affecting the anal canal. Chemoradiotherapy (CRT) is the first-line treatment in nearly all cases, ensuring complete clinical response in up to 80% of patients. Abdominoperineal resection (APR) is typically reserved as salvage therapy in those patients with persistent or recurrent tumor after CRT. In locally advanced tumors, an extralevator abdominoperineal excision (ELAPE), which entails excision of the anal canal and levator muscles, might be indicated to obtain negative resection margins. In this setting, the combination of highly irradiated tissue and large surgical defect increases the risk of developing postoperative perineal wound complications. One of the most dreadful complications is perineal evisceration (PE), which requires immediate surgical treatment to avoid irreversibile organ damage. Different techniques have been described to prevent perineal complications after ELAPE, although none of them have reached consensus. In this technical note, we present a case of PE after ELAPE performed for a recurrent ASCC. Perineal evisceration was approached by combining a uterine retroversion with a gluteal transposition flap to obtain wound healing and reinforcement of the pelvic floor at once, when a mesh placement is not recommended.
肛门鳞状细胞癌(ASCC)是最常见的影响肛管的恶性肿瘤组织学亚型。近所有病例的一线治疗均为放化疗(CRT),高达 80%的患者可实现完全临床缓解。在 CRT 后肿瘤持续或复发的患者中,腹会阴切除术(APR)通常作为挽救性治疗。对于局部晚期肿瘤,为获得阴性切缘可能需要行外括约肌肛门会阴切除术(ELAPE),切除肛管和提肛肌。在此情况下,高剂量照射的组织和大的手术缺损增加了发生术后会阴伤口并发症的风险。最可怕的并发症之一是会阴脱出(PE),需要立即手术治疗,以避免不可逆转的器官损伤。虽然已经描述了许多种预防 ELAPE 后会阴并发症的技术,但尚无一种技术达成共识。在本技术说明中,我们报告了 1 例因复发性 ASCC 而行 ELAPE 后发生 PE 的病例。在不推荐使用网片的情况下,我们通过子宫后倾和臀肌移位瓣联合应用的方法来处理 PE,以实现即刻伤口愈合和盆底加固。