Internal Medicine, McLaren Health Care Corp, Flint, Michigan, USA
Cardiology, University of Nebraska Medical Center, Omaha, NE, USA.
BMJ Case Rep. 2023 Oct 29;16(10):e255993. doi: 10.1136/bcr-2023-255993.
Infective endocarditis caused by in patients without a history of intravenous drug abuse and endovascular procedures is rare. We present a middle-aged man with fever, chills, night sweats and dyspnoea for 2 weeks. Physical examination and blood cultures were drawn, and the patient was empirically started on antibiotics. Unfortunately, the patient experienced progressive clinical deterioration requiring endotracheal intubation and vasopressor support. Transthoracic echocardiogram followed by transesophageal echocardiogram was performed that showed bicuspid aortic valve, severe aortic regurgitation, membranous ventricular septal defect, vegetations on aortic and tricuspid valves, dilated aortic root, and a fistula between the aorta and right atrium. The patient underwent emergent aortic valve and aortic root replacement along with tricuspid commissuroplasty and ventricular septal defect (VSD) closure. Later, intraoperative tissue cultures grew , and antipseudomonal antibiotic coverage was added. This case highlights that can occur without risk factors and can lead to fatal cardiovascular complications.
由 引起、患者无静脉药物滥用和血管内操作史的感染性心内膜炎较为罕见。我们报告一例发热、寒战、盗汗和呼吸困难 2 周的中年男性患者。采集了体格检查和血培养样本,经验性地开始使用抗生素治疗。不幸的是,患者病情逐渐恶化,需要气管插管和血管加压支持。进行了经胸超声心动图检查,随后进行了经食管超声心动图检查,结果显示为二叶主动脉瓣、严重主动脉瓣反流、膜性室间隔缺损、主动脉瓣和三尖瓣上的赘生物、升主动脉扩张,以及主动脉和右心房之间的瘘管。患者接受了紧急主动脉瓣和主动脉根部置换术,以及三尖瓣交界切开术和室间隔缺损(VSD)闭合术。随后,术中组织培养出 ,并加用抗假单胞菌抗生素治疗。本例提示 可在无危险因素的情况下发生,并可导致致命性心血管并发症。