Department of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
School of Stomatology, Qingdao University, Qingdao, 266023, China.
BMC Oral Health. 2023 Oct 29;23(1):820. doi: 10.1186/s12903-023-03344-w.
This study aims to assess the short- and long-term changes in the upper airway and alar width after mini-implant -assisted rapid palatal expansion (MARPE) in nongrowing patients.
Five electronic databases (PubMed, Scopus, Embase, Web of Science, and Cochrane Library) were searched up to 2 August, 2023 based on the PICOS principles. The main outcomes were classified into three groups: 1) nasal cavity changes, 2) upper airway changes and 3) alar changes. The mean difference (MD) and 95% confidence intervals (CI) were used to assess these changes. Heterogeneity tests, subgroup analyses, sensitivity analyses, and publication bias were also analyzed.
Overall, 22 articles were included for data analysis. Nasal cavity width (WMD: 2.05 mm; 95% CI: 1.10, 3.00) and nasal floor width (WMD: 2.13 mm; 95% CI: 1.16, 3.11) increased significantly. While palatopharyngeal volume (WMD: 0.29 cm, 95% CI: -0.44, 1.01), glossopharyngeal volume (WMD: 0.30 cm, 95% CI: -0.29, 0.89) and hypopharyngeal volume (WMD: -0.90 cm; 95% CI: -1.86, 0.06) remained unchanged, nasal cavity volume (WMD: 1.24 cm, 95% CI: 0.68, 1.81), nasopharyngeal volume (MD: 0.75 cm, 95% CI: 0.44, 1.06), oropharyngeal volume (WMD: 0.61 cm, 95% CI: 0.35, 0.87), and total volume of the upper airway (WMD: 1.67 cm, 95% CI: 0.68, 2.66) increased significantly. Alar width (WMD: 1.47 mm; 95% CI: 0.40, 2.55) and alar base width (WMD: 1.54 mm; 95% CI: 1.21, 1.87) also increased.
MARPE can increase nasal cavity width, nasal cavity volume, nasopharyngeal volume and oropharyngeal volume for nongrowing patients, but has no significant effect on hypopharyngeal volume. In addition, the alar width also increased. However, the studies included in this meta-analysis were mainly retrospective, nonrandomized and small in number, so the findings should be interpreted with caution and high-quality RCTs need to be studied.
本研究旨在评估非生长患者接受微型植入物辅助快速腭扩张（MARPE）后上气道和鼻翼宽度的短期和长期变化。
根据 PICOS 原则，检索了五个电子数据库（PubMed、Scopus、Embase、Web of Science 和 Cochrane Library），检索时间截至 2023 年 8 月 2 日。主要结局分为三组：1）鼻腔变化，2）上气道变化和 3）鼻翼变化。使用均数差（MD）和 95%置信区间（CI）评估这些变化。还进行了异质性检验、亚组分析、敏感性分析和发表偏倚分析。
共有 22 篇文章纳入数据分析。鼻腔宽度（WMD：2.05mm；95%CI：1.10，3.00）和鼻底宽度（WMD：2.13mm；95%CI：1.16，3.11）显著增加。然而，腭咽腔容积（WMD：0.29cm，95%CI：-0.44，1.01）、舌咽腔容积（WMD：0.30cm，95%CI：-0.29，0.89）和下咽腔容积（WMD：-0.90cm；95%CI：-1.86，0.06）保持不变，鼻腔容积（WMD：1.24cm，95%CI：0.68，1.81）、鼻咽腔容积（MD：0.75cm，95%CI：0.44，1.06）或口咽腔容积（WMD：0.61cm，95%CI：0.35，0.87）和上气道总容积（WMD：1.67cm，95%CI：0.68，2.66）显著增加。鼻翼宽度（WMD：1.47mm；95%CI：0.40，2.55）和鼻翼基底宽度（WMD：1.54mm；95%CI：1.21，1.87）也增加。
MARPE 可增加非生长患者的鼻腔宽度、鼻腔容积、鼻咽腔容积和口咽腔容积，但对上咽腔容积无显著影响。此外，鼻翼宽度也增加。然而，本荟萃分析纳入的研究主要为回顾性、非随机且数量较少，因此，研究结果应谨慎解读，需要进行高质量的 RCT 研究。
