Department of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
J Vasc Access. 2024 Sep;25(5):1695-1699. doi: 10.1177/11297298231192239. Epub 2023 Oct 29.
Metastatic infections can complicate catheter-related blood stream infections (CRBSI) in dialysis dependent patients. However, an infected/septic aneurysm involving the aorta or its branches as a direct complication of CRBSI without an underlying infective endocarditis is not reported so far in the literature. We report a 43-year female, who presented with CRBSI 2 weeks following a tunneled dialysis catheter (TDC) insertion. Due to the lack of defervescence after 72 h of antibiotics given as per the culture sensitivity reports, the TDC was removed. Blood cultures grew Pseudomonas . After a catheter free interval of 4 days, a TDC was reinserted, an antibiotic course was completed, and she was discharged in stable condition. Five days later, she presented with acute abdominal pain and fever. A tender, firm, and pulsatile mass was noted in the hypogastrium with a bruit. Contrast-enhanced CT revealed a pseudoaneurysm of the aorta, and left common iliac artery at the site of origin. She was started on IV antibiotics and planned for an endovascular prosthesis but had a sudden collapse during her hospital stay due to a ruptured aneurysm. CRBSI due to certain pathogens such as Pseudomonas might require prolonged and dual antibiotic therapy to prevent fulminant complications.
转移性感染可能会使依赖透析的患者并发导管相关血流感染(CRBSI)变得复杂。然而,在目前的文献中,尚未有报道称感染/感染性动脉瘤作为 CRBSI 的直接并发症,累及主动脉或其分支,而没有潜在的感染性心内膜炎。我们报告了一位 43 岁的女性,在隧道式透析导管(TDC)插入后 2 周出现 CRBSI。由于根据培养敏感性报告给予抗生素 72 小时后仍未退烧,因此将 TDC 取出。血培养生长出铜绿假单胞菌。在无导管 4 天后,重新插入 TDC,完成一个疗程的抗生素治疗,然后她病情稳定出院。5 天后,她出现急性腹痛和发热。在下腹部可触及压痛、坚硬且有搏动的肿块,并伴有杂音。增强 CT 显示主动脉和左髂总动脉起源处假性动脉瘤。她开始接受静脉内抗生素治疗,并计划进行血管内假体,但在住院期间突然因动脉瘤破裂而崩溃。CRBSI 由某些病原体引起,如铜绿假单胞菌,可能需要延长和双重抗生素治疗,以防止发生暴发性并发症。