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手术联合高强度聚焦超声治疗梭形细胞肉瘤:一例报告

Managing spindle cell sarcoma with surgery and high-intensity focused ultrasound: A case report.

作者信息

Zhu Ying-Qiong, Zhao Gan-Chao, Zheng Chen-Xi, Yuan Lei, Yuan Geng-Biao

机构信息

Department of Endocrinology, People's Hospital of Fengjie, Fengjie 404600, Chongqing, China.

Department of Oncology, People's Hospital of Fengjie, Fengjie 404600, Chongqing, China.

出版信息

World J Clin Cases. 2023 Sep 26;11(27):6551-6557. doi: 10.12998/wjcc.v11.i27.6551.

Abstract

BACKGROUND

Undifferentiated pleomorphic sarcomas, also known as spindle cell sarcomas, are a relatively uncommon subtype of soft tissue sarcomas in clinical practice.

CASE SUMMARY

We present a case report of a 69-year-old female patient who was diagnosed with undifferentiated spindle cell soft tissue sarcoma on her left thigh. Surgical excision was initially performed, but the patient experienced a local recurrence following multiple surgeries and radioactive particle implantations. High-intensity focused ultrasound (HIFU) was subsequently administered, resulting in complete ablation of the sarcoma without any significant complications other than bone damage at the treated site. However, approximately four months later, the patient experienced a broken lesion at the original location. After further diagnostic workup, the patient underwent additional surgery and is currently stable with a good quality of life.

CONCLUSION

HIFU has shown positive outcomes in achieving local control of limb spindle cell sarcoma, making it an effective non-invasive treatment option.

摘要

背景

未分化多形性肉瘤,也称为梭形细胞肉瘤,在临床实践中是软组织肉瘤中相对不常见的亚型。

病例摘要

我们报告一例69岁女性患者,其左大腿被诊断为未分化梭形细胞软组织肉瘤。最初进行了手术切除,但患者在多次手术和放射性粒子植入后出现局部复发。随后给予高强度聚焦超声(HIFU)治疗,肉瘤完全消融,除治疗部位出现骨损伤外无任何严重并发症。然而,大约四个月后,患者在原部位出现破溃病灶。进一步诊断检查后,患者接受了额外手术,目前病情稳定,生活质量良好。

结论

高强度聚焦超声在实现肢体梭形细胞肉瘤的局部控制方面显示出积极效果,使其成为一种有效的非侵入性治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a95d/10600997/319162ea492b/WJCC-11-6551-g001.jpg

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