Benarous Xavier, Lahaye Hélène, Pellerin Hugues, Consoli Angèle, Cohen David, Labelle Réal, Renaud Johanne, Gérardin Priscille, El-Khoury Fabienne, van der Waerden Judith, Guilé Jean-Marc
Department of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
INSERM Unit U1105 Research Group for Analysis of the Multimodal Cerebral Function, University of Picardy Jules Verne (UPJV), Amiens, France.
Front Psychiatry. 2023 Oct 13;14:1211516. doi: 10.3389/fpsyt.2023.1211516. eCollection 2023.
The high level of emotional problems in youths placed in foster care contrasts with the limited use of evidence-based treatments. This study aims to better characterize the clinical features and therapeutic outcomes of foster care youths with mood disorders.
A secondary analysis of data collected in the context of a French-Canadian clinical research network on pediatric mood disorders in four sites was conducted to compare three groups of patients with depressive or bipolar disorder: those without exposure to child welfare intervention (WCWI, = 181), those who received non-placement psychosocial intervention (NPI, = 62), and those in placement interventions (PI, = 41).
We observed a very high rate of academic problems in patients in the groups NPI/PI compared to those in the WCWI group. Patients in the PI group had more disruptive behavioral disorders (OR = 6.87, 95% CI [3.25-14.52]), trauma-related disorders (OR = 3.78, 95% CI [1.6-8.94]), and any neurodevelopmental disorders (OR = 2.73, 95% CI [1.36-5.49]) compared to the other groups (NPI/WCWI). Among inpatients, the Clinical Global Impression-Improvement scale and the change in the Children Global Assessment Scale during the hospital stay did not differ across the three groups. We observed a higher prescription rate of antipsychotics in the PI group compared to the NPI/WCWI groups, but no significant difference for antidepressants and mood stabilizers.
These findings support the view that, when provided with dedicated support, fostered inpatient youths can improve in a range comparable to other inpatients. Undetected neurodevelopmental disorders and academic problems are likely important contributors of the burden of mood disorders in these youths.
寄养青少年中存在的高水平情绪问题与循证治疗方法的有限使用形成鲜明对比。本研究旨在更好地描述患有情绪障碍的寄养青少年的临床特征和治疗结果。
对在四个地点开展的法语区加拿大儿科情绪障碍临床研究网络中收集的数据进行二次分析,以比较三组患有抑郁症或双相情感障碍的患者:未接受儿童福利干预的患者(WCWI,n = 181)、接受非安置性社会心理干预的患者(NPI,n = 62)和接受安置干预的患者(PI,n = 41)。
与WCWI组相比,我们观察到NPI/PI组患者的学业问题发生率非常高。与其他组(NPI/WCWI)相比,PI组患者有更多的破坏性行为障碍(OR = 6.87,95% CI [3.25 - 14.52])、创伤相关障碍(OR = 3.78,95% CI [1.6 - 8.94])以及任何神经发育障碍(OR = 2.73,95% CI [1.36 - 5.49])。在住院患者中,三组患者在住院期间的临床总体印象改善量表和儿童总体评估量表的变化没有差异。与NPI/WCWI组相比,我们观察到PI组抗精神病药物的处方率更高,但抗抑郁药和心境稳定剂的处方率没有显著差异。
这些发现支持了这样一种观点,即当获得专门支持时,寄养住院青少年的改善程度与其他住院患者相当。未被发现的神经发育障碍和学业问题可能是这些青少年情绪障碍负担的重要促成因素。