Yatsuji Sho, Misumi Yoshitsugu, Tamiya Akiko, Nonaka Kouichi
Department of Digestive Endoscopy Tokyo Women's Medical University Hospital Tokyo Japan.
Department of Otorhinolaryngology-Head and Neck Surgery Tokyo Women's Medical University Hospital Tokyo Japan.
DEN Open. 2023 Oct 26;4(1):e306. doi: 10.1002/deo2.306. eCollection 2024 Apr.
Iodine staining allows for clear visualization of the lesion boundaries of esophageal squamous cell carcinoma and is used as the gold standard for detecting and diagnosing the extent of the cancer. Heartburn and retrosternal pain are known side effects; however, no reports of pharyngitis or laryngitis exist. Therefore, we present a case of laryngitis caused by iodine reflux. An 80-year-old female patient underwent endoscopic submucosal dissection for superficial esophageal cancer. During the operation, a reflux of the iodine used for diagnosing the extent of the lesion occurred, and she experienced laryngitis accompanied by hoarseness postoperatively, which improved with steroid administration. Laryngitis due to iodine reflux may cause airway stenosis, and preventing reflux requires anterograde application of iodine and spraying iodine as gently and locally as possible.
碘染色可清晰显示食管鳞状细胞癌的病变边界，被用作检测和诊断癌症范围的金标准。烧心和胸骨后疼痛是已知的副作用；然而，尚无咽炎或喉炎的相关报道。因此，我们报告一例由碘反流引起的喉炎病例。一名80岁女性患者因浅表食管癌接受了内镜下黏膜下剥离术。手术过程中，用于诊断病变范围的碘发生了反流，术后她出现了伴有声音嘶哑的喉炎，使用类固醇治疗后有所改善。碘反流引起的喉炎可能导致气道狭窄，预防反流需要顺行使用碘，并尽可能轻柔且局部地喷洒碘。
