Hassan Farooq, Khan Asmat Ullah, Zaidi Syed Zahoor Ul Hassan, Niazi Madiha Khan, Ismail Muhammad Amjed
PHC punjab healthcare commission, Lahore, Pakistan.
Department of Eastern Medicine, Faculty of Medical and Health Sciences, University of Poonch, Rawalakot, Pakistan.
Dose Response. 2023 Oct 25;21(4):15593258231210431. doi: 10.1177/15593258231210431. eCollection 2023 Oct-Dec.
The aerobic organisms not only need oxygen for survival, but oxygen is also fundamentally malignant to the aerobic organism on the grounds of free radical generation and their affiliation with free oxidative stress. This study was done to evaluate the antioxidant and protective properties of , , , , and against lipid peroxidation induced by different pro-oxidants. The aqueous extracts of these medicinal plants showed inhibition against thiobarbituric acid reactive species (TBARS) induced by different pro-oxidants (10 mM FeSO4 and 5 mM sodium nitroprusside) in the brain and liver of mice. Moreover, the free radical scavenging activities of the extracts were evaluated by the scavenging of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. , , and showed higher inhibitory effects, which could be attributed to their significantly reduced ability and free radical scavenging activities. Therefore, the oxidative stress in the brain and liver could be potentially managed or prevented by the dietary intake of , , and plants, which justifies the use of these plants in various degenerative diseases. and showed relatively weak antioxidant activities.
需氧生物不仅生存需要氧气,而且基于自由基的产生及其与自由基氧化应激的关联,氧气对需氧生物从根本上来说也是有害的。本研究旨在评估[植物名称1]、[植物名称2]、[植物名称3]、[植物名称4]和[植物名称5]对不同促氧化剂诱导的脂质过氧化的抗氧化和保护特性。这些药用植物的水提取物对小鼠脑和肝中由不同促氧化剂(10 mM硫酸亚铁和5 mM硝普钠)诱导的硫代巴比妥酸反应性物质(TBARS)表现出抑制作用。此外,通过清除2,2-二苯基-1-苦基肼(DPPH)自由基来评估提取物的自由基清除活性。[植物名称1]、[植物名称2]和[植物名称3]表现出更高的抑制作用,这可能归因于它们显著降低的[具体能力]和自由基清除活性。因此,通过饮食摄入[植物名称1]、[植物名称2]和[植物名称3]植物可能潜在地控制或预防脑和肝中的氧化应激,这证明了这些植物在各种退行性疾病中的应用合理性。[植物名称4]和[植物名称5]表现出相对较弱的抗氧化活性。