混合性自身免疫性溶血性贫血与胃癌的罕见关联。
A Rare Association of Mixed Autoimmune Hemolytic Anemia with Gastric Carcinoma.
作者信息
Chinnadurai Anu, Strum Scott, Ghassemian Artin, Fortin Dalilah, Foster Cheryl, Breadner Daniel
机构信息
Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
London Regional Cancer Program, London Health Sciences Centre, Victoria Hospital, London, ON, Canada.
出版信息
Case Rep Oncol. 2023 Oct 20;16(1):1209-1216. doi: 10.1159/000534278. eCollection 2023 Jan-Dec.
This case report outlines a 70-year-old female patient who presented with a concurrent mixed autoimmune hemolytic anemia (AIHA) and a gastric adenocarcinoma. Her treatment course of these two diseases is summarized, which included supportive care, neoadjuvant chemotherapy for her gastric adenocarcinoma, steroids, rituximab, and surgical resection of the tumor. This approach ultimately led to the stabilization of her AIHA and primary cure for her solid malignancy. We briefly review both AIHA and gastric adenocarcinoma as clinical entities, propose working causes of hemolytic anemia including gastric adenocarcinoma, and outline a successful treatment pathway for these two concurrent conditions.
本病例报告概述了一名70岁女性患者，她同时患有混合性自身免疫性溶血性贫血（AIHA）和胃腺癌。总结了她这两种疾病的治疗过程，包括支持治疗、胃腺癌的新辅助化疗、类固醇、利妥昔单抗以及肿瘤的手术切除。这种治疗方法最终使她的AIHA病情稳定，并使实体恶性肿瘤得到了初步治愈。我们简要回顾了AIHA和胃腺癌这两种临床病症，提出了包括胃腺癌在内的溶血性贫血的可能病因，并概述了这两种并发疾病的成功治疗途径。
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