• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

血液透析患者因……导致的导管相关血流感染

Catheter-Related Bloodstream Infection in Hemodialysis Patient due to .

作者信息

Hristova Preslava M, Alexandrova Alexandra S, Lucanov Martin, Hitkova Hristina Y, Borisov Biser Kirilov

机构信息

Department of Microbiology and Virology, Medical University - Pleven, Pleven, Bulgaria.

Department of Medical Microbiology, Medical University of Sofia, Sofia, Bulgaria.

出版信息

Case Rep Nephrol Dial. 2023 Sep 20;13(1):142-147. doi: 10.1159/000533581. eCollection 2023 Jan-Dec.

DOI:10.1159/000533581
PMID:37900930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10601877/
Abstract

, previously known as , is a rare causative agent of human infections. Several reports testify that the most frequently infected patients are immunosuppressed, especially those undergoing hemodialysis. A 34-year-old man with an end-stage renal disease complained of chills, fever, and general fatigue at the end of a regular hemodialysis session. The echocardiographic examination showed vegetation located on the dialysis catheter in the right atrium. Empirical therapy was initiated with intravenous gentamicin, and after the isolation of the agent, the treatment was continued with intravenous imipenem/cilastatin. The blood cultures and the tip of the replaced catheter were positive for , identified by Vitek 2 Compact. Verification of the automated identification was performed using 16S sequencing. The 16S sequence product was used to query the NCBI bacterial database and revealed 99.75% identity to that of strain CIP 103176 16S ribosomal RNA in the NCBI GenBank database. The antimicrobial susceptibility results revealed resistance to aminopenicillins and susceptibility to all other tested antimicrobials. To our knowledge, this is the first report of catheter-related vegetation with echocardiographic confirmation and the successful eradication of infection in a patient undergoing hemodialysis with imipenem/cilastatin.

摘要

以前称为 ,是人类感染的一种罕见病原体。几份报告证明,最常感染的患者是免疫抑制患者,尤其是那些正在接受血液透析的患者。一名患有终末期肾病的34岁男子在一次常规血液透析结束时抱怨发冷、发烧和全身乏力。超声心动图检查显示右心房的透析导管上有赘生物。开始经验性使用静脉注射庆大霉素治疗,在分离出病原体后,继续使用静脉注射亚胺培南/西司他丁治疗。血培养和更换导管的尖端对 通过Vitek 2 Compact鉴定为 呈阳性。使用16S测序对自动鉴定进行验证。16S序列产物用于查询NCBI细菌数据库,结果显示与NCBI GenBank数据库中 菌株CIP 103176的16S核糖体RNA有99.75%的同一性。抗菌药敏结果显示对氨基青霉素耐药,对所有其他测试抗菌药物敏感。据我们所知,这是第一份经超声心动图证实的导管相关赘生物以及使用亚胺培南/西司他丁成功根除血液透析患者 感染的报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de8/10601877/7105023e75b0/cnd-2023-0013-0001-533581_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de8/10601877/bac99a1d4ce7/cnd-2023-0013-0001-533581_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de8/10601877/7105023e75b0/cnd-2023-0013-0001-533581_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de8/10601877/bac99a1d4ce7/cnd-2023-0013-0001-533581_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3de8/10601877/7105023e75b0/cnd-2023-0013-0001-533581_F02.jpg

相似文献

1
Catheter-Related Bloodstream Infection in Hemodialysis Patient due to .血液透析患者因……导致的导管相关血流感染
Case Rep Nephrol Dial. 2023 Sep 20;13(1):142-147. doi: 10.1159/000533581. eCollection 2023 Jan-Dec.
2
Phylogenetics of family Enterobacteriaceae and proposal to reclassify Escherichia hermannii and Salmonella subterranea as Atlantibacter hermannii and Atlantibacter subterranea gen. nov., comb. nov.肠杆菌科系统发育及将赫尔曼埃希氏菌和地下沙门氏菌重新分类为赫尔曼阿特兰蒂杆菌和地下阿特兰蒂杆菌的提议,新属,新组合
Microbiol Immunol. 2016 May;60(5):303-11. doi: 10.1111/1348-0421.12374.
3
Catheter Related Escherichia hermannii Sepsis in a Haemodialysis Patient.一名血液透析患者发生与导管相关的赫氏埃希菌败血症
Open Microbiol J. 2016 Feb 2;10:1-3. doi: 10.2174/1874285801610010001. eCollection 2016.
4
Draft genome sequence of an clinical strain isolated from human muscle tissue.
Microbiol Resour Announc. 2024 Jan 17;13(1):e0085623. doi: 10.1128/mra.00856-23. Epub 2023 Dec 8.
5
First case of bloodstream infection caused by NDM-positive Escherichia hermannii.产新德里金属β-内酰胺酶(NDM)阳性赫氏埃希菌血流感染 1 例
BMC Infect Dis. 2023 May 25;23(1):355. doi: 10.1186/s12879-023-08336-3.
6
PICC-associated infection with : A case report and review of the literature.经外周静脉穿刺中心静脉置管相关感染:一例病例报告及文献综述
IDCases. 2018 Aug 23;13:4. doi: 10.1016/j.idcr.2018.e00444. eCollection 2018.
7
Undetectable Production of the VIM-1 Carbapenemase in an Clinical Isolate.临床分离株中VIM-1碳青霉烯酶的不可检测性产生
Front Microbiol. 2021 Dec 20;12:741972. doi: 10.3389/fmicb.2021.741972. eCollection 2021.
8
[Femoral hemodialysis catheter-related bacteremia due to Globicatella sanguinis: challenges in species identification].[因血源环球菌引起的股静脉血液透析导管相关菌血症:菌种鉴定中的挑战]
Mikrobiyol Bul. 2017 Apr;51(2):177-182. doi: 10.5578/mb.53821.
9
"Locking in" a rare pathogen.“锁定”一种罕见病原体。
Indian J Med Microbiol. 2022 Apr-Jun;40(2):311-314. doi: 10.1016/j.ijmmb.2022.02.001. Epub 2022 Feb 23.
10
ESBL-producing harboring a plasmid encoding IS up and down stream of ,, and isolated from an edible river fish.携带一种编码位于上下游的插入序列的质粒且从食用河鱼中分离出的产超广谱β-内酰胺酶(ESBL)菌株 。 (你提供的原文似乎表述不完整且存在一些混淆,翻译可能不太准确,最好能进一步完善原文以便更精准翻译。)
Microbiol Resour Announc. 2024 Jun 11;13(6):e0005624. doi: 10.1128/mra.00056-24. Epub 2024 Apr 30.

引用本文的文献

1
Isolation and Characterization of Colistin-Resistant from Foods in Two Italian Regions in the South of Italy.意大利南部两个地区食品中耐黏菌素菌株的分离与鉴定
Microorganisms. 2025 Jan 14;13(1):163. doi: 10.3390/microorganisms13010163.

本文引用的文献

1
KDOQI Clinical Practice Guideline for Vascular Access: 2019 Update.KDIGO 临床实践指南:血管通路 2019 更新版。
Am J Kidney Dis. 2020 Apr;75(4 Suppl 2):S1-S164. doi: 10.1053/j.ajkd.2019.12.001. Epub 2020 Mar 12.
2
as the sole cause of osteomyelitis in a patient with an open tibial shaft fracture.作为一名开放性胫骨干骨折患者骨髓炎的唯一病因。
BMJ Case Rep. 2019 Nov 26;12(11):e231206. doi: 10.1136/bcr-2019-231206.
3
Infections in Humans: A Systematic Review.人类感染:系统评价
Trop Med Infect Dis. 2019 Jan 21;4(1):17. doi: 10.3390/tropicalmed4010017.
4
PICC-associated infection with : A case report and review of the literature.经外周静脉穿刺中心静脉置管相关感染:一例病例报告及文献综述
IDCases. 2018 Aug 23;13:4. doi: 10.1016/j.idcr.2018.e00444. eCollection 2018.
5
Preservation of residual kidney function in hemodialysis patients: reviving an old concept.维持血液透析患者的残余肾功能:重拾一个古老的概念。
Kidney Int. 2016 Aug;90(2):262-271. doi: 10.1016/j.kint.2016.02.037. Epub 2016 May 12.
6
Catheter Related Escherichia hermannii Sepsis in a Haemodialysis Patient.一名血液透析患者发生与导管相关的赫氏埃希菌败血症
Open Microbiol J. 2016 Feb 2;10:1-3. doi: 10.2174/1874285801610010001. eCollection 2016.
7
Phylogenetics of family Enterobacteriaceae and proposal to reclassify Escherichia hermannii and Salmonella subterranea as Atlantibacter hermannii and Atlantibacter subterranea gen. nov., comb. nov.肠杆菌科系统发育及将赫尔曼埃希氏菌和地下沙门氏菌重新分类为赫尔曼阿特兰蒂杆菌和地下阿特兰蒂杆菌的提议,新属,新组合
Microbiol Immunol. 2016 May;60(5):303-11. doi: 10.1111/1348-0421.12374.
8
Pyelonephritis Caused Solely by Escherichia hermanii.仅由赫氏埃希菌引起的肾盂肾炎。
Jundishapur J Microbiol. 2014 May;7(5):e18138. doi: 10.5812/jjm.18138. Epub 2014 May 1.
9
Emerging Escherichia pathogen.新兴的大肠杆菌病原体。
J Clin Microbiol. 2013 Aug;51(8):2785-6. doi: 10.1128/JCM.00983-13. Epub 2013 Jun 5.
10
Biofilm-like structures and pathogenicity of Escherichia hermannii YS-11, a clinical isolate from a persistent apical periodontitis lesion.来自持续性根尖周炎病变临床分离株赫氏埃希菌YS-11的生物膜样结构与致病性
FEMS Immunol Med Microbiol. 2010 Aug;59(3):456-65. doi: 10.1111/j.1574-695X.2010.00700.x. Epub 2010 May 17.