肾活检专栏：淀粉样变性
Kidney Biopsy Corner: Amyloidosis.
作者信息
Biederman Laura E, Dasgupta Alana D, Dreyfus Darren E, Nadasdy Tibor, Satoskar Anjali A, Brodsky Sergey V
机构信息
Department of Pathology, Ohio State Wexner Medical Center, Columbus, OH, USA.
Department of Pathology, Nationwide Children's Hospital, Columbus, OH, USA.
出版信息
Glomerular Dis. 2023 Sep 8;3(1):165-177. doi: 10.1159/000533195. eCollection 2023 Jan-Dec.
Amyloidosis is an infiltrative disease caused by misfolded proteins depositing in tissues. Amyloid infiltrates the kidney in several patterns. There are, as currently described by the International Society of Amyloidosis, 14 types of amyloid that can involve the kidney, and these types may have different locations or clinical settings. Herein we report a case of AA amyloidosis occurring in a 24-year-old male with a history of intravenous drug abuse and provide a comprehensive review of different types of amyloids involving the kidney.
淀粉样变性是一种由错误折叠的蛋白质沉积在组织中引起的浸润性疾病。淀粉样物质以多种模式浸润肾脏。正如国际淀粉样变性协会目前所描述的，有14种类型的淀粉样物质可累及肾脏，这些类型可能有不同的部位或临床情况。在此，我们报告一例发生在一名有静脉药物滥用史的24岁男性身上的AA型淀粉样变性病例，并对累及肾脏的不同类型淀粉样物质进行全面综述。
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