Scripps Bighorn Mohs Surgery and Dermatology Center, La Jolla, California.
Cutis. 2023 Sep;112(3):E6-E10. doi: 10.12788/cutis.0856.
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) and primary cutaneous mucinous carcinoma (PCMC) are rare low-grade neoplasms thought to arise from apocrine glands that share many histological features and are proposed to be on a single histopathologic continuum, with EMPSGC as the in situ form that may progress to the invasive PCMC. Management involves a metastatic workup and either wide local excision (WLE) with greater than 5 mm margins or Mohs micrographic surgery (MMS) in anatomically sensitive areas. We present 2 cases of EMPSGC and 3 cases of PCMC and review their clinical and histopathologic features, differential diagnoses, and treatment.
内分泌黏液性汗腺癌（EMPSGC）和原发性皮肤黏液腺癌（PCMC）是罕见的低级别肿瘤，被认为起源于顶泌汗腺，具有许多组织学特征，被认为是单一的组织病理学连续体，EMPSGC 为原位形式，可能进展为侵袭性 PCMC。治疗包括进行转移灶检查，对于解剖学敏感区域，采用大于 5mm 切缘的广泛局部切除术（WLE）或 Mohs 显微外科手术（MMS）。我们报告了 2 例 EMPSGC 和 3 例 PCMC，并复习了它们的临床和组织病理学特征、鉴别诊断和治疗。
