腹侧口部丘脑深部脑刺激对一名音乐家肌张力障碍患者的影响：病例说明

Effects of ventro-oral thalamic deep brain stimulation in a patient with musician's dystonia: illustrative case.

作者信息

Poncelet Fauve, Smeets Sara, Taira Takaomi, Visser-Vandewalle Veerle, Vandenberghe Wim, Peeters Jana, Van Bogaert Tine, Nuttin Bart

机构信息

Departments of1Neurosurgery.

3Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

J Neurosurg Case Lessons. 2023 Oct 30;6(18). doi: 10.3171/CASE22569.

DOI:10.3171/CASE22569

PMID:37903422

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10618068/

Abstract

BACKGROUND

Musician's dystonia is a task-specific focal hand dystonia characterized by involuntary contraction of muscles while playing a musical instrument. Current treatment options are often insufficient.

OBSERVATIONS

We present the effects of ventro-oral thalamic deep brain stimulation in a patient with musician's dystonia. The patient was a 67-year-old pianist with musician's dystonia who underwent deep brain stimulation with the ventralis oralis anterior and posterior nuclei of the thalamus as targets. The Tubiana and Chamagne rating scale was used to evaluate the effects of stimulation. The outcome was evaluated independently by four clinicians in a blinded manner at 3 months postoperatively. There was a distinct reduction of symptoms during stimulation. At 15 months postoperatively, the beneficial effect remained. No lasting side effects were observed.

LESSONS

Further studies are warranted to evaluate the safety and long-term efficacy of this treatment modality.

摘要

背景

音乐家肌张力障碍是一种特定任务性局灶性手部肌张力障碍，其特征为在演奏乐器时肌肉不自主收缩。目前的治疗选择往往并不充分。

观察结果

我们展示了丘脑腹口部深部脑刺激对一名音乐家肌张力障碍患者的疗效。该患者是一名67岁患有音乐家肌张力障碍的钢琴家，接受了以丘脑腹前核和腹后核为靶点的深部脑刺激。使用图比亚纳和沙马涅评分量表评估刺激效果。术后3个月，由四名临床医生以盲法独立评估结果。刺激期间症状明显减轻。术后15个月，有益效果依然存在。未观察到持久的副作用。