Sipehia R, Chawla A S, Chang T M
Biomaterials. 1986 Nov;7(6):471-3. doi: 10.1016/0142-9612(86)90038-4.
Plasma surface modification technique was used to add amino groups onto the surfaces of polypropylene beads by exposing them to anhydrous ammonia plasma. Through these amino groups, albumin was attached to the polypropylene beads. Attached albumin was further stabilized by crosslinking with glutaraldehyde. The effect of washing albuminated polypropylene beads with saline and human plasma was investigated. It was found that after initial rapid removal of albumin, the concentration of attached albumin tended to reach a steady-state. After 52 h of washing, the amount of albumin retained on the beads varied between 125 and 171 micrograms/cm2.
采用等离子体表面改性技术，通过将聚丙烯珠暴露于无水氨等离子体中，在其表面添加氨基。通过这些氨基，白蛋白附着在聚丙烯珠上。附着的白蛋白通过与戊二醛交联进一步稳定。研究了用盐水和人血浆洗涤白蛋白化聚丙烯珠的效果。结果发现，在最初快速去除白蛋白后，附着白蛋白的浓度趋于达到稳态。洗涤52小时后，珠子上保留的白蛋白量在125至171微克/平方厘米之间变化。
