Suppr超能文献

翻修踝关节置换术的存活率。

Survival of revision ankle arthroplasty.

机构信息

University Hospitals Plymouth NHS Trust, Plymouth, UK.

Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.

出版信息

Bone Joint J. 2023 Nov 1;105-B(11):1184-1188. doi: 10.1302/0301-620X.105B11.BJJ-2023-0199.R1.

Abstract

AIMS

The number of revision total ankle arthroplasties (TAAs) which are undertaken is increasing. Few studies have reported the survival after this procedure. The primary aim of this study was to analyze the survival of revision ankle arthroplasties using large datasets. Secondary aims were to summarize the demographics of the patients, the indications for revision TAA, further operations, and predictors of survival.

METHODS

The study combined data from the National Joint Registry and NHS Digital to report the survival of revision TAA. We have previously reported the failure rates and risk factors for failure after TAA, and the outcome of fusion after a failed TAA, using the same methodology. Survival was assessed using life tables and Kaplan Meier graphs. Cox proportional hazards regression models were fitted to compare failure rates.

RESULTS

A total of 228 patients underwent revision TAA. The mean follow-up was 2.6 years (SD 2.0). The mean time between the initial procedure and revision was 2.3 years (SD 1.8). The most commonly used implant was the Inbone which was used in 81 patients. A total of 29 (12.7%) failed; nine (3.9%) patients underwent a further revision, 19 (8.3%) underwent a fusion, and one (0.4%) had an amputation. The rate of survival was 95.4% (95% confidence interval (CI) 91.6 to 97.5) at one year, 87.7% (95% CI 81.9 to 91.7; n = 124) at three years and 77.5% (95% CI 66.9 to 85.0; n = 57) at five years. Revision-specific implants had a better survival than when primary implants were used at revision. A total of 50 patients (21.9%) had further surgery; 19 (8.3%) underwent reoperation in the first 12 months. Cox regression models were prepared. In crude analysis the only significant risk factors for failure were the use of cement (hazard ratio (HR) 3.02 (95% CI 1.13 to 8.09)) and the time since the primary procedure (HR 0.67 (95% CI 0.47 to 0.97)). No risk factors for failure were identified in multivariable Cox regression modelling.

CONCLUSION

Revision TAAs have good medium term survival and low rates of further surgery. New modular revision implants appear to have improved the survival compared with the use of traditional primary implants at revision.

摘要

目的

接受翻修全踝关节置换术(TAA)的数量正在增加。很少有研究报告过这种手术后的存活率。本研究的主要目的是使用大型数据集分析翻修踝关节置换术的存活率。次要目的是总结患者的人口统计学资料、翻修 TAA 的指征、进一步的手术以及存活率的预测因素。

方法

本研究结合了国家关节登记处和 NHS 数字的数据,报告了翻修 TAA 的存活率。我们之前使用相同的方法报告了 TAA 后的失败率和失败风险因素,以及 TAA 失败后的融合结果。使用寿命表和 Kaplan-Meier 图评估存活率。拟合 Cox 比例风险回归模型以比较失败率。

结果

共有 228 名患者接受了翻修 TAA。平均随访时间为 2.6 年(SD 2.0)。初次手术和翻修之间的平均时间为 2.3 年(SD 1.8)。使用最广泛的植入物是 Inbone,有 81 名患者使用。共有 29 例(12.7%)失败;9 例(3.9%)患者接受了进一步翻修,19 例(8.3%)接受了融合,1 例(0.4%)接受了截肢。一年时的生存率为 95.4%(95%CI 91.6 至 97.5),三年时为 87.7%(95%CI 81.9 至 91.7;n=124),五年时为 77.5%(95%CI 66.9 至 85.0;n=57)。与初次使用时相比,特定于翻修的植入物具有更好的存活率。共有 50 名患者(21.9%)接受了进一步手术;19 名(8.3%)在最初 12 个月内再次手术。准备了 Cox 回归模型。在粗分析中,失败的唯一显著危险因素是使用水泥(风险比(HR)3.02(95%CI 1.13 至 8.09))和初次手术后的时间(HR 0.67(95%CI 0.47 至 0.97))。多变量 Cox 回归模型未确定失败的危险因素。

结论

翻修 TAA 具有良好的中期存活率和较低的进一步手术率。新型模块化翻修植入物似乎比初次使用时传统的原发性植入物提高了存活率。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验