Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine.
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston.
Clin Obstet Gynecol. 2023 Dec 1;66(4):825-840. doi: 10.1097/GRF.0000000000000821. Epub 2023 Sep 22.
With an increasing incidence of twin gestations, understanding the inherent risks associated with these pregnancies is essential in modern obstetrics. The unique differences in placentation in monochorionic twins leads to unique complications, including twin-to-twin transfusion syndrome, the twin anemia-polycythemia sequence, and selective fetal growth restriction. Not only does the understanding of the monochorionic placenta lead to an understanding of the pathophysiology of the complications of monochorionic twins, but it also has led to the development of highly effective directed fetal therapy via fetoscopic laser coagulation used in twin-to-twin transfusion syndrome.
随着双胞胎妊娠发生率的增加,了解这些妊娠相关的固有风险在现代产科中至关重要。单绒毛膜双胞胎胎盘的独特差异导致了独特的并发症,包括双胎输血综合征、双胎贫血-多血症序列和选择性胎儿生长受限。对单绒毛膜胎盘的理解不仅导致了对单绒毛膜双胞胎并发症病理生理学的理解,而且还导致了通过使用胎儿镜激光凝固治疗双胎输血综合征的高效定向胎儿治疗的发展。