Department of Clinical Laboratory, Weifang People's Hospital, Weifang, People's Republic of China.
Hematology. 2023 Dec;28(1):2277498. doi: 10.1080/16078454.2023.2277498. Epub 2023 Nov 2.
The sigma metric offers a quantitative framework for evaluating process performance in clinical laboratories. This study aimed to evaluate the analytical performance of automated analysers in haematology laboratories, using the sigma metric to choose the best analyser as an internal reference analyser.
internal quality control (IQC) data were collected for 6 months from SNCS, and the sigma value was calculated for 9 haematology analysers in the laboratory.
For the normal control level, a satisfactory mean sigma value ≥3 was observed for all of the studied parameters of all automated analysers. For the low control level, platelet (PLT) count by Instrument (Inst.) G performed poorly, with a mean sigma value <3. Inst. H, with all parameters' sigma values >4, performed best and was chosen as the internal reference analyser.
The sigma metric can be used as a guide to choose the QC strategy and plan QC frequency. It can facilitate the comparison of the same assay performed by multiple systems.
西格玛度量为临床实验室的过程性能评估提供了一个定量框架。本研究旨在使用西格玛度量来选择最佳分析仪作为内部参考分析仪，评估血液学实验室中自动化分析仪的分析性能。
从 SNCS 收集了 6 个月的内部质量控制（IQC）数据，并计算了实验室中 9 台血液学分析仪的西格玛值。
对于正常控制水平，所有研究参数的所有自动化分析仪的平均西格玛值均≥3，观察到令人满意的结果。对于低控制水平，仪器（Inst.）G 检测血小板（PLT）计数的表现不佳，平均西格玛值<3。所有参数的西格玛值均>4 的 Inst. H 表现最佳，被选为内部参考分析仪。
西格玛度量可用于指导选择 QC 策略和计划 QC 频率。它可以促进多个系统进行的相同检测的比较。
