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2022 年 AFU 结石委员会推荐意见:医学管理——从诊断到治疗。

2022 Recommendations of the AFU Lithiasis Committee: Medical management - from diagnosis to treatment.

机构信息

Hospices Civils de Lyon, SFNDT, SP, Lyon, France.

Nephrology Department, Clinique Saint-Exupéry, SFNDT, Toulouse, France.

出版信息

Prog Urol. 2023 Nov;33(14):911-953. doi: 10.1016/j.purol.2023.08.004.

Abstract

The morphological-compositional analysis of urinary stones allows distinguishing schematically several situations: dietary, digestive, metabolic/hormonal, infectious and genetic problems. Blood and urine testing are recommended in the first instance to identify risk factors of urinary stone disease in order to avoid recurrence or progression. The other objective is to detect a potential underlying pathology associated with high risk of urinary stone disease (e.g. primary hyperparathyroidism, primary or enteric hyperoxaluria, cystinuria, distal renal tubular acidosis) that may require specific management. Lifestyle-diet measures are the basis of the management of all stone types, but pharmacological treatments may be required. METHODOLOGY: These recommendations were developed using two methods: the Clinical Practice Recommendation (CPR) method and the ADAPTE method, depending on whether the question was considered in the European Association of Urology (EAU) recommendations (https://uroweb.org/guidelines/urolithiasis) [EAU 2022] and their adaptability to the French context.

摘要

尿石的形态-成分分析可大致区分以下几种情况:饮食、消化、代谢/激素、感染和遗传问题。建议进行血液和尿液检查,以确定尿石病的风险因素,从而避免复发或进展。另一个目的是检测与尿石病高风险相关的潜在基础病理(例如甲状旁腺功能亢进症、原发性或肠性高草酸尿症、胱氨酸尿症、远端肾小管酸中毒),可能需要特定的治疗。生活方式-饮食措施是所有结石类型治疗的基础,但可能需要药物治疗。方法:这些建议使用两种方法制定:临床实践推荐(CPR)方法和 ADAPTE 方法,具体取决于该问题是否被考虑在欧洲泌尿外科学会(EAU)建议中(https://uroweb.org/guidelines/urolithiasis)[EAU 2022]及其对法国国情的适应性。

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