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Pharmacokinetic drug-drug interaction between olaparib and apixaban: a case report.

作者信息

Berge M, Giraud J S, De Percin S, Puszkiel A, Thomas-Schoemann A, Blanchet B

机构信息

Department of Clinical Pharmacy, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris, CARPEM, 75014, Paris, France.

Department of Medical Oncology, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris, CARPEM, 75014, Paris, France.

出版信息

Cancer Chemother Pharmacol. 2024 May;93(5):519-521. doi: 10.1007/s00280-023-04606-8. Epub 2023 Nov 3.

DOI:10.1007/s00280-023-04606-8
PMID:37921902
Abstract
摘要

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本文引用的文献

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Inhibition of efflux transporters by poly ADP-ribose polymerase inhibitors.聚ADP-核糖聚合酶抑制剂对转运蛋白外排的抑制作用
Basic Clin Pharmacol Toxicol. 2023 Oct;133(4):428-436. doi: 10.1111/bcpt.13928. Epub 2023 Aug 24.
2
Do Apixaban Plasma Levels Relate to Bleeding? The Clinical Outcomes and Predictive Factors for Bleeding in Patients with Non-Valvular Atrial Fibrillation.阿哌沙班血浆水平与出血有关吗？非瓣膜性心房颤动患者出血的临床结局及预测因素。
Biomedicines. 2022 Aug 18;10(8):2001. doi: 10.3390/biomedicines10082001.
3
2022 international clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer, including patients with COVID-19.
2022 年国际癌症患者静脉血栓栓塞症治疗和预防临床实践指南，包括 COVID-19 患者。
Lancet Oncol. 2022 Jul;23(7):e334-e347. doi: 10.1016/S1470-2045(22)00160-7.
4
Tyrosine kinase inhibitors and direct oral anticoagulants: In vitro evaluation of drug-drug interaction mediated by P-glycoprotein.酪氨酸激酶抑制剂和直接口服抗凝剂：P-糖蛋白介导的药物相互作用的体外评价。
Fundam Clin Pharmacol. 2022 Oct;36(5):860-868. doi: 10.1111/fcp.12769. Epub 2022 Feb 28.
5
Apixaban concentration variability and relation to clinical outcomes in real-life patients with atrial fibrillation.真实世界心房颤动患者中阿哌沙班浓度变异性及其与临床结局的关系。
Sci Rep. 2021 Jul 6;11(1):13908. doi: 10.1038/s41598-021-93372-9.
6
The real world use of combined P-glycoprotein and moderate CYP3A4 inhibitors with rivaroxaban or apixaban increases bleeding.利伐沙班或阿哌沙班与 P-糖蛋白和中度 CYP3A4 抑制剂联合使用的真实世界数据增加了出血风险。
J Thromb Thrombolysis. 2020 May;49(4):636-643. doi: 10.1007/s11239-020-02037-3.
7
Apixaban: A Clinical Pharmacokinetic and Pharmacodynamic Review.阿哌沙班：临床药代动力学和药效学评价。
Clin Pharmacokinet. 2019 Oct;58(10):1265-1279. doi: 10.1007/s40262-019-00775-z.
8
Physiologically Based Pharmacokinetic Modeling for Olaparib Dosing Recommendations: Bridging Formulations, Drug Interactions, and Patient Populations.奥拉帕利给药建议的基于生理学的药代动力学建模：桥接制剂、药物相互作用和患者人群。
Clin Pharmacol Ther. 2019 Jan;105(1):229-241. doi: 10.1002/cpt.1103. Epub 2018 Aug 9.
9
Rapid determination of apixaban concentration in human plasma by liquid chromatography/tandem mass spectrometry: application to pharmacokinetic study.采用液相色谱/串联质谱法快速测定人血浆中阿哌沙班浓度及其在药代动力学研究中的应用。
J Pharm Biomed Anal. 2013 May 5;78-79:150-3. doi: 10.1016/j.jpba.2013.02.007. Epub 2013 Feb 20.