Efficient one-pot syntheses of secondary amines from nitro aromatics and benzyl alcohols over Pd/NiTi-LDH under visible light.

Solar energy-induced cascade/tandem reactions in one-pot are sustainable and green. Herein, the Pd/NiTi-LDH nanocomposite, with Pd nanoparticles (NPs) (∼3-6 nm) deposited on NiTi-LDH nanosheets, was obtained and was applied in the reaction between nitro aromatics and alcohols to synthesize secondary amines under visible light. The superior performance observed over the as-obtained Pd/NiTi-LDH nanocomposite for this reaction can be attributed to a successful merging of Pd-based hydrogenation and LDH-based photocatalysis, in which consecutive light-induced hydrogenation of nitro compounds to amines, dehydrogenation of alcohols to aldehydes, condensation between the formed aldehydes and amines to imines and the hydrogenation of final imines to generate the desired secondary amines were realized in one pot over Pd/NiTi-LDH under visible light. This work shows an effective and green strategy in the synthesis of secondary amines. This study also demonstrates the high potential of using metal/LDH nanocomposites for light-initiated organic syntheses.