I Kh Almadhoun Mohammed Khaleel, Hattab Abdallah Wasel, Alazzeh Nemer Nedal, Aladwan Sufyan Taleb, Ta'amneh Osamah
Medicine and Surgery, Mutah University, Al-Karak, JOR.
Neurosurgery, Mutah University, Al-Karak, JOR.
Cureus. 2023 Oct 6;15(10):e46564. doi: 10.7759/cureus.46564. eCollection 2023 Oct.
Dandy-Walker Syndrome (DWS) is a rare congenital neurological condition characterized by cerebellar and posterior fossa malformations, often presenting a variable clinical spectrum. Common complications include hydrocephalus, necessitating interventions like ventriculoperitoneal (VP) shunts, and endoscopic third ventriculostomy (ETV). We describe the case of a five-month-old infant conceived through in vitro fertilization (IVF), initially presenting with cold-like symptoms, later diagnosed with DWS. The patient underwent VP shunt placement for hydrocephalus management, with subsequent complications requiring shunt revisions and ETV. Vigilant monitoring and timely interventions were crucial for a favorable outcome, highlighting the challenges in diagnosing and managing DWS and the importance of tailored treatment strategies.
丹迪-沃克综合征（DWS）是一种罕见的先天性神经系统疾病，其特征为小脑和后颅窝畸形，临床表现往往多样。常见并发症包括脑积水，需要进行脑室腹腔（VP）分流术和内镜下第三脑室造瘘术（ETV）等干预措施。我们描述了一例通过体外受精（IVF）受孕的5个月大婴儿的病例，该婴儿最初出现类似感冒的症状，后来被诊断为DWS。患者因脑积水接受了VP分流术，随后出现的并发症需要对分流器进行修订和ETV治疗。严密监测和及时干预对于取得良好预后至关重要，这凸显了DWS诊断和管理中的挑战以及量身定制治疗策略的重要性。
