Department of Clinical Sciences, Division of Surgery, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Department of Medical Sciences, Uppsala University and Uppsala University Hospital, Uppsala, Sweden.
Scand J Gastroenterol. 2024 Jan-Jun;59(2):176-182. doi: 10.1080/00365521.2023.2278422. Epub 2024 Jan 30.
The Swedish National Patient Register (SNPR) is frequently used in studies of colonic diverticular disease (DD). Despite this, the validity of the coding for this specific disease in the register has not been studied.
From SNPR, 650 admissions were randomly identified encoded with ICD 10, K572-K579. From the years 2002 and 2010, 323 and 327 patients respectively were included in the validation study. Patients were excluded prior to, or up to 2 years after a diagnosis with IBD, Celiac disease, IBS, all forms of colorectal cancer (primary and secondary), and anal cancer. Medical records were collected and data on clinical findings with assessments, X-ray examinations, endoscopies and laboratory results were reviewed. The basis of coding was compared with internationally accepted definitions for colonic diverticular disease. Positive predictive values (PPV) were calculated.
The overall PPV for all diagnoses and both years was 95% (95% CI: 93-96). The PPV for the year 2010 was slightly higher 98% (95% CI: 95-99) than in the year 2002, 91% (95% CI: (87-94) which may be due to the increasing use of computed tomography (CT).
The validity of DD in SNPR is high, making the SNPR a good source for population-based studies on DD.
瑞典国家患者登记处(SNPR)常用于结肠憩室疾病(DD)的研究。尽管如此,该登记处对这种特定疾病的编码的准确性尚未得到研究。
从 SNPR 中,随机选择了编码为 ICD 10 的 K572-K579 的 650 例住院病例。在 2002 年和 2010 年,分别有 323 例和 327 例患者纳入验证研究。在诊断为炎症性肠病(IBD)、乳糜泻、肠易激综合征、所有类型的结直肠癌(原发性和继发性)和肛门癌之前或之后 2 年内,排除了这些患者。收集了病历,并对临床发现、评估、X 射线检查、内窥镜检查和实验室结果进行了审查。将编码的依据与国际公认的结肠憩室疾病定义进行了比较。计算了阳性预测值(PPV)。
所有诊断和两个年份的总体 PPV 为 95%(95%置信区间:93-96)。2010 年的 PPV 略高,为 98%(95%置信区间:95-99),而 2002 年的 PPV 为 91%(95%置信区间:(87-94),这可能是由于计算机断层扫描(CT)的使用增加所致。
SNPR 中 DD 的有效性很高,这使得 SNPR 成为研究 DD 的人群基础研究的良好来源。