Khan Sher Bahadar, Ghaffar Rehmat, Adil Muhammad, Jan Muneeb Ullah
Sher Bahadar Khan Associate Professor, Intervention Cardiologist, Lady Reading Hospital, Peshawar, Pakistan.
Rehmat Ghaffar Assistant Professor, Cardiac Imaging, MTI Hayatabad Medical Complex, Peshawar, Pakistan.
Pak J Med Sci. 2023 Nov-Dec;39(6):1657-1660. doi: 10.12669/pjms.39.6.8008.
The objective of this study was to determine the diagnostic value of stress perfusion CMR for the detection of coronary artery disease.
The was a retrospective cross sectional study in which 43 subjects were included from Cardiac MRI unit in the Hayatabad Medical Complex, Peshawar for study from 1 April 2020 to 30 November 2020. All the subjects who had been referred for stress perfusion CMR with suspected CAD were included in the study. Cardiac MRI both at rest and with adenosine stress perfusion was performed which was followed by invasive coronary angiography.
A total of 43 patients were enrolled for the detection or exclusion CAD who underwent stress perfusion CMRI and invasive coronary artery angiography. The study revealed strong and statistically significant association between positive stress perfusion CMR and positive coronary angiogram vs negative stress perfusion CMR and negative coronary angiogram (p= value 0.0001).
Stress perfusion CMRI can be considered as a first line, relatively safe, noninvasive test with significant accuracy to diagnose coronary artery disease in patients with suspected CAD without subjecting these patients to invasive coronary angiogram.
本研究的目的是确定应力灌注心脏磁共振成像（CMR）对检测冠状动脉疾病的诊断价值。
这是一项回顾性横断面研究，从白沙瓦哈亚塔巴德医疗中心的心脏磁共振成像科室纳入了43名受试者，研究时间为2020年4月1日至2020年11月30日。所有因疑似冠心病而被转诊进行应力灌注CMR的受试者均纳入研究。进行了静息和腺苷负荷下的心脏磁共振成像检查，随后进行了有创冠状动脉造影。
共有43例患者被纳入检测或排除冠心病的研究，他们接受了应力灌注CMRI和有创冠状动脉造影。研究显示，阳性应力灌注CMR与阳性冠状动脉造影之间，以及阴性应力灌注CMR与阴性冠状动脉造影之间存在强烈且具有统计学意义的关联（p值 = 0.0001）。
对于疑似冠心病的患者，应力灌注CMRI可被视为一线相对安全的无创检查，在诊断冠状动脉疾病方面具有显著准确性，无需让这些患者接受有创冠状动脉造影。
