Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, People's Republic of China.
Eur J Med Res. 2023 Nov 8;28(1):494. doi: 10.1186/s40001-023-01481-0.
The treatment of lumbar spinal synovial cysts (LSCs) which are relatively rare but can cause neurogenic dysfunction and intractable pain has been a controversial topic for many years. Surgical excision of LSCs is the standard treatment for patients in whom conservative treatment options fail. This meta-analysis was undertaken to compare clinical outcomes between minimally invasive approaches using tubular retractors (microscopic vs. endoscopic) and traditional percutaneous approaches for LSCs. Studies reporting surgical management of LSCs were searched in the Cochrane Library, PubMed and Web of Science database. This meta-analysis was reported following the PRISMA Statement, registered in Prospero (CRD42021288992). A total of 1833 patients were included from both the related relevant studies (41 studies, n = 1831) and the present series (n = 2). Meta-analysis of minimally invasive tubular approaches revealed no statistically significant difference in pain improvement, dural tear, residual cyst, recurrence and operation time between minimal groups with traditional groups (p > 0.05). Minimal groups had better Functional improvement of 100% (95% CI 1.00-1.00; p < 0.001, I = 75.3%) and less reoperation rates of 0% (95% CI - 0.00-0.00; p = 0.007, I = 47.1%). Postoperative length of hospital stay and intraoperative bleeding in minimal groups were also less than traditional groups (p < 0.05). Subgroup analysis revealed endoscopic groups had less operation time (p = 0.004), and there was no significant difference in the rest. For patients with LSCs but without obvious clinical and imaging evidence of vertebral instability, even when preoperative stable grade 1 spondylolisthesis is present, minimally invasive tubular approaches without fusion may provide the best outcome in surgical management.
腰椎滑膜囊肿(Lumbar Spinal Synovial Cysts,LSCs)的治疗一直是一个备受争议的话题,尽管它相对罕见,但可引起神经功能障碍和顽固性疼痛。对于保守治疗失败的患者,手术切除 LSCs 是标准治疗方法。本荟萃分析旨在比较使用管状牵开器(显微镜下与内窥镜下)的微创方法与传统经皮方法治疗 LSCs 的临床疗效。在 Cochrane 图书馆、PubMed 和 Web of Science 数据库中搜索了报道 LSCs 手术治疗的研究。本荟萃分析按照 PRISMA 声明进行报告,并在 Prospero(CRD42021288992)中进行了注册。从相关研究(41 项研究,n=1831)和本系列研究(n=2)中总共纳入了 1833 例患者。微创管状入路的荟萃分析显示,微创组与传统组在疼痛改善、硬脊膜撕裂、残余囊肿、复发和手术时间方面无统计学差异(p>0.05)。微创组的功能改善率更好,为 100%(95%CI 1.00-1.00;p<0.001,I²=75.3%),再次手术率更低,为 0%(95%CI -0.00-0.00;p=0.007,I²=47.1%)。微创组的术后住院时间和术中出血量也少于传统组(p<0.05)。亚组分析显示,内窥镜组的手术时间更短(p=0.004),其他方面无显著差异。对于没有明显临床和影像学不稳定证据的 LSCs 患者,即使存在术前稳定的 1 度脊椎滑脱,不融合的微创管状入路可能是手术治疗的最佳选择。